[Effect of C27-steroids on lipid peroxidation in rat liver mitochondria]. / Vplyv C27-steroïdiv na peroksydne okyslennia lipidiv u mitokhondriiakh pechinky shchuriv.

The influence of C27-steroids--vitamin D3 and 20-hydroxyecdysone in free-radical reactions on lipid peroxidation in the mitochondrial fraction of rat's liver has been studied. Antioxidant activity of superoxide dismutase and catalase and the content of lipid components--cholesterol and phospholipids has been determined. The assumption was put forward that antioxidant action of steroids was possible as a result of to the modification of mitochondrial membrane through its lipid content and changing of its cholesterol: phospholipids content.