ABSTRACT
Interrelationships between parameters of humoral immunity with AB0 blood groups have been investigated. The highest content of IgA to transglutaminase was found in A(II) patients, while the lowest content was found in AB(IV) patients. The blood content on anti-gliadin IgA was higher in healthy donors. The oral liquid of periodontic patients contained anti-gliadin IgA and IgB lacking in healthy donors. It have been found that 47% of healthy people and 52.7% of patients are infcted with Helicobacter pylori. In the group of periodontic patients A(II) individually predominated; they were characterized by the presence of antibodies to H. pylori in the oral liquid, these antibodies were absent in healthy donors. The pepsinogen level was higher in blood of periodontic patients than in healthy donors. B(III) patients had the lowest level of blood pepsinogen.
Subject(s)
ABO Blood-Group System , Chronic Periodontitis/blood , Chronic Periodontitis/immunology , Immunity, Humoral , Adult , Chronic Periodontitis/enzymology , Chronic Periodontitis/microbiology , Female , Gliadin/immunology , Helicobacter Infections/enzymology , Helicobacter Infections/immunology , Helicobacter Infections/microbiology , Helicobacter pylori/immunology , Humans , Immunoglobulin A/blood , Immunoglobulin A/immunology , Immunoglobulin G/blood , Immunoglobulin G/immunology , Male , Phenotype , Saliva/immunology , Transglutaminases/immunology , Young AdultABSTRACT
Hydrogen peroxide has been found to have a distorting effect on the quality of determination of the serological markers of hepatitis B and C, transglutaminase antibodies: an increase in the percent of false higher (anti-HBsAg, HBeAg, anti-HCV) and false lower (anti-HBeAg) values, and on the results of PCR-based diagnosis (PCR inhibition that was more pronounced especially in low viremia). A possibility of interference of measurement results in the blood metabolite pool should be taken into account in the use of high-technology methods of laboratory analysis. In particular, there may be changes in the detection of immunological and molecular biological methods in hyperpyruvatemia and hyperoxaloacetatemia, with elevated peroxide concentrations during pathological processes.
Subject(s)
Hepatitis B, Chronic/blood , Hepatitis C, Chronic/blood , Biomarkers/blood , Electrochemical Techniques , Ethanol/blood , False Negative Reactions , False Positive Reactions , Hepatitis B Antibodies/blood , Hepatitis B Antigens/blood , Hepatitis B, Chronic/virology , Hepatitis C Antibodies/blood , Hepatitis C, Chronic/virology , Humans , Hydrogen Peroxide/blood , Immunoenzyme Techniques , Immunoglobulin A/blood , Immunoglobulin G/blood , Luminescent Measurements , Oxaloacetates/blood , Polymerase Chain Reaction , Pyruvic Acid/blood , Transglutaminases/immunologyABSTRACT
The performed studies provided new evidence for biological variability in clinically important analytes, estimated a possible association of the metabolic features and the conservative genetic attribute--the ABO blood group. Certain features in the levels of protein, carbohydrate, lipid, and mineral metabolic parameters were revealed in relation to various blood groups.
Subject(s)
ABO Blood-Group System/blood , Blood Proteins/analysis , Carbohydrates/blood , Lipids/blood , Minerals/blood , Female , Humans , MaleABSTRACT
In work the data are presented, which characterize the connection of a diet with disease of illnesses of digestive organs which rises in process of increase of products that contain gluten and meat reduction in diet. Immune reaction is found out, that shows the appearance of antibodies. A gladin and fabric transglutaminaze. Reaction characteristics are different in people with different blood groups.
