ABSTRACT
The new dihydropyridine calcium antagonist isradipine versus nifedipine was tested in 41 patients with essential hypertension and cerebrovascular insufficiency. The tests have shown that isradipine shows all hemodynamic effects by significantly improving cerebral blood flow and it is better tolerated than nifedipine. It is concluded that isradipine is an effective agent in the long-term management of hypertensive patients at a high risk for cerebral hypoperfusion.
Subject(s)
Cerebrovascular Circulation/drug effects , Cerebrovascular Disorders/drug therapy , Hemodynamics/drug effects , Hypertension/drug therapy , Isradipine/therapeutic use , Adult , Aged , Cerebrovascular Disorders/physiopathology , Chronic Disease , Drug Evaluation , Drug Tolerance , Female , Humans , Hypertension/physiopathology , Male , Middle Aged , Nifedipine/therapeutic useABSTRACT
The determination of mean time of transport of an agent in radionuclide phlebography is technically a simple and highly effective method of diagnosis of diseases of the lower limb veins that can be effectively used in all hospitals, fitted out with gamma-cameras with a computerized system.
Subject(s)
Leg/blood supply , Veins/diagnostic imaging , Adult , Female , Humans , Male , Middle Aged , Radionuclide Imaging , Regional Blood Flow , Technetium Tc 99m Aggregated Albumin , Veins/physiologyABSTRACT
The paper is concerned with analysis of a method of dynamic esophageal scintigraphy modified by the authors for diagnosis and control of therapy of reflux esophagitis combined with duodenal ulcer in 33 patients aged 17 to 72. The proposed method is technically simple, highly effective and can be recommended for use in hospitals equipped with computer-assisted gamma-cameras. Indices of radionuclide clearance of the esophagus reflect its function of self-purification and well correlate with a degree of inflammatory changes of esophageal mucosa. They disappear more rapidly in patients receiving multimodality therapy including selective drug denervation of the stomach than in patients on conservative therapy alone.
Subject(s)
Esophagitis, Peptic/diagnostic imaging , Esophagoscopy , Esophagus/diagnostic imaging , Organotechnetium Compounds , Adolescent , Adult , Aged , Combined Modality Therapy , Duodenal Ulcer/diagnostic imaging , Duodenal Ulcer/physiopathology , Duodenal Ulcer/therapy , Esophagitis, Peptic/physiopathology , Esophagitis, Peptic/therapy , Esophagus/physiopathology , Female , Humans , Male , Middle Aged , Organometallic Compounds , Peristalsis , Phytic Acid , Technetium , Tomography, Emission-Computed/methodsABSTRACT
Computerized emission tomography of the brain is an atraumatic and highly informative technique for diagnosis of metastatic brain tumours. The above method is of major practical significance as a primary test in diagnosing metastases in the brain in cases of clinical neurological symptom complex.
Subject(s)
Brain Neoplasms/diagnostic imaging , Brain/diagnostic imaging , Tomography, Emission-Computed , Brain Neoplasms/secondary , Breast Neoplasms/pathology , Female , Humans , Lung Neoplasms/pathology , Sodium Pertechnetate Tc 99m , Tomography, X-Ray ComputedABSTRACT
Diagnostic potentialities of emission computerized tomography (ECT), computerized tomography (CT) and polyposition scintigraphy (PS) were established by the results of a comprehensive study of the liver in 105 cancer patients with 246 metastatic tumors. In the foci with a diameter less than 20 mm ECT and PS were ineffective, in 20-40 mm ECT and CT potentialities were approximately the same and 50% of detection was noted with PS; in 40 mm and over the diagnostic potentialities of the above 3 methods were equal.
