Not only a therapeutic target; mTOR in Hodgkin lymphoma and acute lymphoblastic leukemia.

Introduction: The mechanistic/mammalian target of rapamycin (mTOR) is a serine/threonine kinase, which is downregulated or upregulated and is implicated in different types of cancer including hematologic neoplasms, skin prostate, and head and neck cancer. Aim: The aim of this study was to explore the current knowledge of mTOR signaling in acute lymphoblastic leukemia and Hodgkin lymphoma. Methods: A systematic review was performed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, searching PubMed, Discovery Service for National Autonomous University of Mexico, Registro Nacional de Instituciones y Empresas Científicas y Tecnológicas (RENIECYT), and Scientific Electronic Library Online (SciELO) from 1994 to 2023. A total of 269 papers were identified for acute lymphoblastic leukemia, but based on specific criteria, 15 were included; for Hodgkin lymphoma, 110 papers were identified, but 5 were included after manual searching. Results: A total of 20 papers were evaluated, where mTOR activity is increased in patients with Hodgkin lymphoma and acute lymphoblastic leukemia by different molecular mechanisms. Conclusions: mTOR activity is increased in patients with both hematologic neoplasms and NOTCH; interleukin 4, 7, and 9, and nuclear proteins have been studied for their role in the activation of mTOR signaling.

Description of a Novel Pathogenic Variant in the ARPC1B and a Severe Allergy in Two Infants.

Actinrelated protein 2/3 complex subunit 1B (ARPC1B) deficiency is an inborn error of immunity (IEI) characterized by a combination of immunodeficiency and immune dysregulation and classified as an IEI with allergic manifestations. Here, we describe two patients with pathogenic variants in the ARPC1B gene. The first patient presented with eczema and bronchospasm at six months of age. The second patient presented with eczema and milk protein allergy at five months of age. The c.899_944 (p.Glu300Glyfs*7) pathogenic variant was previously described, whereas the c.863del (p.Pro288Leufs*9) variant was novel. ARPC1B deficiency should be considered because of the severe allergic manifestations at an early age.

Diffuse intrinsic pontine gliomas: First registry effort in Mexico.

INTRODUCTION: Brainstem tumors comprise 10.9% of all brain tumors, and pediatric diffuse intrinsic pontine gliomas (DIPG) have a fatal prognosis. Some countries have developed national and international register databases to characterize their populations to aid clinical and public policy decisions. This study provides information regarding the clinical characteristics of a retrospective cohort of children with DIPG in México from 2001 to 2021, and assesses the proposed prognostic factors previously described for survival outcome. METHODS: Health institutions from Mexico were invited to contribute to a retrospective electronic registry of patients with DIPG based on the International DIPG Registry. Fisher's exact test was used to compare long- and short-term survivors. Overall survival was estimated using the Kaplan-Meier method. Differences between survival curves were evaluated using the log-rank test and Cox proportional hazard regression analysis. RESULTS: Total 110 patients were included. The median age of the patients at diagnosis was 7 years. Sixty patients (54.5%) presented with symptoms in less than 6 months; the most frequent symptom was ataxia (56.4%). Ninety patients received treatment (81.8%), the overall survival at 4 years was 11.4%, and 16 patients (14.5%) were admitted for palliative end-of-life care. We found no significant survival differences for any of the prognostic factors. CONCLUSION: This study highlights the need to develop strategies to standardize healthcare processes and enhance the quality of care to improve clinical diagnosis in Mexico. We also observed a barrier to the acceptance of palliative end-of-life care in the family and medical teams.

Effects of a Physical Exercise Program on the Physical Capacities of Older Adults: A Quasi-Experimental Study.

Purpose: To measure the effects of an exercise program on the physical capacities of older adults such as strength, flexibility, balance, and aerobic capacity. Patients and Methods: This was a quasi-experimental study on a population of 5550 older adults and a sample of 4830 participants in an active aging program designed by the Municipal Health Secretary. The exercise program lasted 12 months, and pre-and post-program intervention measures were recorded using the senior fitness test. Results: Most participants were women (92.4%) and their mean age was 70.7 years (standard deviation, 7.3 years; range, 60-97 years). All areas showed significant differences before and after the program in terms of the participants' physical capabilities (p < 0.05), muscular strength and flexibility had a more significant mean difference and a large effect (>0.80), except for aerobic capacity, which had a small effect. Conclusion: The present study revealed that a supervised physical exercise program at the community level has positive effects on the physical capacities of coordination, balance, flexibility, strength, and aerobic capacity, which are essential components for a better functional capacity at this stage of life, with improvements that encompassed the improved self-perception of their health status, a reduction of overweight and obesity. The reinforcement of these programs is recommended, consequently, promoting pre-sport games and sports championships among the elderly population, as a public health strategy.

Identificación de un brote de SARSCoV-2 (Covid-19) en un centro gerontológico de la Ciudad de México.

OBJECTIVE: To describe a Covid-19 outbreak in a gerontological center in Mexico City. MATERIAL AND METHODS: Cross-sectional study in older adults. The association of risk factors for dying from Covid-19 was analyzed using a multiple logistic regression model. RESULTS: One hundred and two elders with an average age of 82.5 ± 8.8 years were included. Fifty-five (54%) tested positive and 47 (46%) were negative for the new coronavirus. Using the multiple logistic regression model, people with frailty had an OR of 11.6 of dying from Covid-19 compared to robust people (p-value = 0.024). CONCLUSION: The Covid-19 outbreak was initially caused by a resident of the center and spread by cross infection. In vulnerable populations, early detection, isolation, and follow-up of contacts should be carried out, as well as the identification of risk factors in order to reduce the spread and mortality caused by SARSCoV-2.

Enteroparasitosis en escolares, problema de salud pública. Intervención desde el Sistema Nacional Integrado de Salud de Uruguay / Intestinal parasites in schoolchildren, public health problem. Intervention from the National Integrated Health System of Uruguay

RESUMEN Objetivos Generar un modelo de intervención en promoción de salud, desde el Sistema Nacional Integrado de Salud (SNIS) de Uruguay, con promotores escolares de salud, recursos web y abordaje desde los centros educativos a la comunidad. Materiales y Métodos Estudio descriptivo transversal, de base poblacional, mediante un muestreo aleatorio, no agrupado, durante los meses de abril y diciembre de 2016. Se llevó a cabo una capacitación para escolares en promoción de salud, encuesta poblacional, herramientas web, exámenes parasitológicos y georreferenciación. Resultados Se observaron prevalencias de giardiasis, del 14% (IC95%: 11-17) (6,5 a 22%); y oxiurosis 26% (IC95: 22-30) (20 a 44%). Se visualizaron 45 conglomerados de geohelmintiasis (HTS), la mayoría en zonas con asentamientos poblacionales carentes de servicios básicos. Conclusiones La existencia de sectores poblacionales vulnerables con índices de contaminación fecal intradomiciliaria y ambientales hace necesario que el SNIS realice de forma sistemática actividades de promoción de salud que puedan aportar datos relevantes para intervenciones gubernamentales intersectoriales y para mejorar la salud de estos sectores desprotegidos.

ABSTRACT Objectives To generate a model of intervention, from the National Integrated Health System (NIHS, Uruguay), with school facilitators of health, web resources and approach from the schools to the community. Materials and Methods Descriptive cross-sectional study of population base using a random sampling, non-clustered, during the months of April and December 2016. This was based in the model of schoolchildren health promoters, the use of web resources and community approach with the school as the centre of actions. Results The prevalence of parasites was 14% for Giardiasis (6,5 and 22%) (IC95%: 11-17) and 26% for Oxiurosis (IC95%: 22-30) (20 and 44%). Soil transmitted helminthiases were geo-referenced: we found 45 clusters, mainly in slums without basic services. Conclusions These worrying results show that there are regions in Montevideo (Uruguay) with high levels of faecal home and environmental contamination. Community approaches with prevention activities from NIHS may have a positive impact on these vulnerable populations.

Paracoccidioidomicosis: reporte de un caso clínico / Paracoccidioidomycosis: a case report / Paracoccidioidomicose: relato de caso

Resumen: La paracoccidioidomicosis es una micosis profunda sistémica, endémica en algunos países de Latinoamérica, sin embargo en Uruguay es poco frecuente y está estrechamente vinculada a la ocupación del paciente. Se describe el caso clínico de un hombre de 26 años, monteador, inmunocompetente, que se presentó clínicamente con linfadenopatías, lesiones cutáneo mucosas y sintomatología respiratoria de evolución subaguda; como hallazgos radiológicos presentó infiltrados perihiliares bilaterales e imagen en halo invertido. Desde el punto de vista micológico se evidenció la presencia del microorganismo en diversas muestras biológicas: biopsias de lesiones orofaríngeas y estudio micológico de lesiones de piel, con serología positiva para Paracoccidioides brasiliensis. Se realizó tratamiento dirigido con antimicótico intravenoso presentando buena respuesta al mismo con mejoría clínica. El abordaje del paciente fue realizado por un equipo multidisciplinario conformado por Otorrinolaringología, Parasitología y Micología, Anatomía patológica, Infectología, Salud Ocupacional y Medicina Interna.

Abstract: Paracoccidioidomycosis is a deep systemic mycosis, endemic in some Latin American countries, however in Uruguay it is rare and is closely linked to patient occupation. The clinical case of a 26-year-old man, immunocompetent, who presented clinically with lymphadenopathy, mucous skin lesions and respiratory symptoms of subacute evolution is described; As radiological findings, it presented bilateral perihilar infiltrates and inverted halo image. From the mycological point of view, the presence of the microorganism in several biological samples was evidenced: biopsies of oropharyngeal lesions and mycological study of skin lesions, with positive serology for Paracoccidioides brasiliensis. Targeted treatment with intravenous antifungal was performed presenting good response to it with clinical improvement. The patient was approached by a multidisciplinary team made up of Otolaryngology, Parasitology and Mycology, Pathology, Infectology, Occupational Health and Internal Medicine.

Resumo: A paracoccidioidomicose é uma micose sistêmica profunda, endêmica em alguns países da América Latina, porém no Uruguai é rara e está intimamente ligada à ocupação do paciente. É descrito o caso clínico de um homem de 26 anos, imunocompetente, que apresentou clinicamente linfadenopatia, lesões de mucosa da pele e sintomas respiratórios de evolução subaguda; Como achados radiológicos, apresentou infiltrados peri-hilares bilaterais e imagem invertida do halo. Do ponto de vista micológico, foi evidenciada a presença do microrganismo em várias amostras biológicas: biópsias de lesões orofaríngeas e estudo micológico de lesões cutâneas, com sorologia positiva para Paracoccidioides brasiliensis. O tratamento direcionado com antifúngico intravenoso foi realizado, apresentando boa resposta a ele com melhora clínica. O paciente foi abordado por uma equipe multidisciplinar composta por Otorrinolaringologia, Parasitologia e Micologia, Patologia, Infectologia, Saúde do Trabalhador e Medicina Interna.

An Engineered Device for Indoleacetic Acid Production under Quorum Sensing Signals Enables Cupriavidus pinatubonensis JMP134 To Stimulate Plant Growth.

The environmental effects of chemical fertilizers and pesticides have encouraged the quest for new strategies to increase crop productivity with minimal impacts on the natural medium. Plant growth promoting rhizobacteria (PGPR) can contribute to this endeavor by improving fitness through better nutrition acquisition and stress tolerance. Using the neutral (non PGPR) rhizobacterium Cupriavidus pinatubonensis JMP134 as the host, we engineered a regulatory forward loop that triggered the synthesis of the phytohormone indole-3-acetic acid (IAA) in a manner dependent on quorum sensing (QS) signals. Implementation of the device in JMP134 yielded synthesis of IAA in an autoregulated manner, improving the growth of the roots of inoculated Arabidopsis thaliana. These results not only demonstrated the value of the designed genetic module, but also validated C. pinatubonensis JMP134 as a suitable vehicle for agricultural applications, as it is amenable to genetic manipulations.

Enteroparasitosis en niños de dos Centros de Atención a la Infancia y la Familia (CAIF) del barrio Casavalle, Montevideo / Children enteroparasitosis in Centers for Child and Family Care (CAIF) in Casavalle neighborhood, Montevideo

Las enteroparasitosis son enfermedades del tubo digestivo causadas por protozoarios, hongos y/o helmintos. Afectan principalmente a niños con condiciones socioeconómicas desfavorables, pudiendo tener repercusión sobre el crecimiento y desarrollo. Con el objetivo de contribuir a generar conocimiento sobre la prevalencia de las enteroparasitosis en niños de dos Centros de Atención a la Infancia y la Familia (CAIF) del barrio Casavalle, zona de influencia de la Policlínica Los Ángeles (Montevideo), entre marzo y diciembre de 2015, se realizaron coproparasitarios y espátulas adhesivas a niños mayores de 6 meses y menores de 5 años. Se devolvieron los resultados a las comunidades participantes, al centro de salud de referencia y a las autoridades de la zona. Se planificaron y realizaron jornadas de formación y sensibilización sobre las parasitosis, aportando información para su prevención. Los niños que tuvieron resultados positivos fueron tratados en la policlínica o derivados para su tratamiento. De los 577 niños matriculados, participaron en el proyecto 317 (54,9%), a todos los cuales se les realizaron los estudios coproparasitario y espátula adhesiva. Resultaron positivos 97 niños (30,6%), de los cuales 22 poliparasitados (6,9%). Los agentes más frecuentemente encontrados fueron: Giardia lamblia (18,6%), Ascaris lumbricoides (6,6%) y Enterobius vermicularis (5,7 %). Se evidenciaron tres mecanismos de transmisión con vía de entrada oral: por contaminación fecal, por contacto con el suelo y transmisión directa, por lo que son necesarios esfuerzos para mejorar hábitos de higiene personal, vigilancia epidemiológica con georreferenciación y acciones dirigidas a mejorar la salud ambiental y saneamiento.

Quorum-Sensing Systems in the Plant Growth-Promoting Bacterium Paraburkholderia phytofirmans PsJN Exhibit Cross-Regulation and Are Involved in Biofilm Formation.

Quorum-sensing systems play important roles in host colonization and host establishment of Burkholderiales species. Beneficial Paraburkholderia species share a conserved quorum-sensing (QS) system, designated BraI/R, that controls different phenotypes. In this context, the plant growth-promoting bacterium Paraburkholderia phytofirmans PsJN possesses two different homoserine lactone QS systems BpI.1/R.1 and BpI.2/R.2 (BraI/R-like QS system). The BpI.1/R.1 QS system was previously reported to be important to colonize and produce beneficial effects in Arabidopsis thaliana plants. Here, we analyzed the temporal variations of the QS gene transcript levels in the wild-type strain colonizing plant roots. The gene expression patterns showed relevant differences in both QS systems compared with the wild-type strain in the unplanted control treatment. The gene expression data were used to reconstruct a regulatory network model of QS systems in P. phytofirmans PsJN, using a Boolean network model. Also, we examined the phenotypic traits and transcript levels of genes involved in QS systems, using P. phytofirmans mutants in homoserine lactone synthases genes. We observed that the BpI.1/R.1 QS system regulates biofilm formation production in strain PsJN and this phenotype was associated with the lower expression of a specific extracytoplasmic function sigma factor ecf26.1 gene (implicated in biofilm formation) in the bpI.1 mutant strain.

Biochemical and Genetic Bases of Indole-3-Acetic Acid (Auxin Phytohormone) Degradation by the Plant-Growth-Promoting Rhizobacterium Paraburkholderia phytofirmans PsJN.

Several bacteria use the plant hormone indole-3-acetic acid (IAA) as a sole carbon and energy source. A cluster of genes (named iac) encoding IAA degradation has been reported in Pseudomonas putida 1290, but the functions of these genes are not completely understood. The plant-growth-promoting rhizobacterium Paraburkholderia phytofirmans PsJN harbors iac gene homologues in its genome, but with a different gene organization and context than those of P. putida 1290. The iac gene functions enable P. phytofirmans to use IAA as a sole carbon and energy source. Employing a heterologous expression system approach, P. phytofirmans iac genes with previously undescribed functions were associated with specific biochemical steps. In addition, two uncharacterized genes, previously unreported in P. putida and found to be related to major facilitator and tautomerase superfamilies, are involved in removal of an IAA metabolite called dioxindole-3-acetate. Similar to the case in strain 1290, IAA degradation proceeds through catechol as intermediate, which is subsequently degraded by ortho-ring cleavage. A putative two-component regulatory system and a LysR-type regulator, which apparently respond to IAA and dioxindole-3-acetate, respectively, are involved in iac gene regulation in P. phytofirmans These results provide new insights about unknown gene functions and complex regulatory mechanisms in IAA bacterial catabolism. IMPORTANCE: This study describes indole-3-acetic acid (auxin phytohormone) degradation in the well-known betaproteobacterium P. phytofirmans PsJN and comprises a complete description of genes, some of them with previously unreported functions, and the general basis of their gene regulation. This work contributes to the understanding of how beneficial bacteria interact with plants, helping them to grow and/or to resist environmental stresses, through a complex set of molecular signals, in this case through degradation of a highly relevant plant hormone.

Neumonitis por hipersensibilidad asociado al cuidado de aves / Hypersensitivity pneumonitis associated to birds care

La neumonitis por hipersensibilidad asociada al cuidado de las aves es uno de los tipos más frecuentes de esta que se presentan. Aunque no se tienen datos epidemiológicos claros sobre su prevalencia, en los hospitales llegan casos de este tipo. No es una patología muy común; sin embargo, una muestra representativa de la población se encuentra expuesta a las aves y, consecuentemente, a los antígenos que causan la enfermedad. Su diagnóstico temprano puede significar para el paciente evitar daños, al dejar de exponerse al antígeno; por el contrario, si no se realiza un diagnóstico temprano, puede generarse un daño pulmonar irreversible. En este artículo, se presenta un caso clínico de neumonitis por hipersensibilidad al cuidado de aves.

Hypersensitivity pneumonitis associated to birds care, is one of the most common types of pneumonitis. Although there is no clear epidemiological data of prevalence, many cases of pneumonitis arrive to hospitals. It is a very rare disorder, however, much of the population is exposed to birds and consequently to antigens that cause this disease. The early diagnosis can mean a reversible damage to the patient if stop exposure to the antigen, but otherwise if the diagnosis isn't made early, can generate an irreversible lung damage. In this paper, it is presented a case of hypersensitivity pneumonitis in birds care.

Nivel de purificación del agua utilizada en clínicas odontológicas universitarias / Level of water Purification that used the Odontological Clinics University

Las aguas que se utilizan en las clínicas odontológicas deberían estar libres de contaminantes y aceites, para asegurar la calidad en los trabajos realizados. Objetivo: Determinar el contaminante en el agua del sistema de las sillas odontológicas en la UNAH-VS. Materiales y métodos: Estudio transversal, cualitativo y cuantitativo, realizado del 18 de marzo al 4 de abril 2014. Exámenes realizados con la ayuda de un laboratorio privado mediante técnicas de recolección de aguas, utilizando previamente métodos de asepsias para eliminar todo microorganismo proveniente del exterior y no del agua específicamente del grifo, mangueras y ozonificador para mayor certeza del estudio. Las muestras fueron tomadas en el lavador de la clínica grande de la facultad de odontología, ozonificador colocado arriba del mismo y silla odontológica contigua al mismo lavador. Resultados: Los exámenes demostraron que el agua del grifo contiene 47% de recuento total bacteriano y 86.13% de dureza; en el ozonificador se encontró 15% de recuento total bacteriano y 81.17% de dureza total y el agua de la silla odontológica refleja 100% en recuento total bacteriano y 83.95% de dureza total del agua. Conclusiones: El grado de contaminación del agua de las clínicas odontológicas es mayor cuando sale por las mangueras de las sillas odontológicas, la cual va directamente a la boca del paciente. El ozonificador realiza un trabajo eficiente al reducir la dureza del agua así como también el recuento bacteriano...(AU)

Effects of the plant growth-promoting bacterium Burkholderia phytofirmans PsJN throughout the life cycle of Arabidopsis thaliana.

Plant growth-promoting rhizobacteria (PGPR) induce positive effects in plants, such as increased growth or reduced stress susceptibility. The mechanisms behind PGPR/plant interaction are poorly understood, as most studies have described short-term responses on plants and only a few studies have analyzed plant molecular responses under PGPR colonization. Here, we studied the effects of the PGPR bacterial model Burkholderiaphytofirmans PsJN on the whole life cycle of Arabidopsis thaliana plants. We reported that at different plant developmental points, strain PsJN can be found in the rhizosphere and also colonizing their internal tissues. In early ontogeny, strain PsJN increased several growth parameters and accelerated growth rate of the plants. Also, an Arabidopsis transcriptome analysis revealed that 408 genes showed differential expression in PsJN-inoculated plants; some of these genes are involved in stress response and hormone pathways. Specifically, genes implicated in auxin and gibberellin pathways were induced. Quantitative transcriptional analyses of selected genes in different developmental stages revealed that the beginning of these changes could be evidenced early in development, especially among the down-regulated genes. The inoculation with heat-killed bacteria provoked a more severe transcriptional response in plants, but was not able to induce plant growth-promotion. Later in ontogeny, the growth rates of inoculated plants decreased with respect to the non-inoculated group and, interestingly, the inoculation accelerated the flowering time and the appearance of senescence signs in plants; these modifications correlate with the early up-regulation of flowering control genes. Then, we show that a single inoculation with a PGPR could affect the whole life cycle of a plant, accelerating its growth rate and shortening its vegetative period, both effects relevant for most crops. Thus, these findings provide novel and interesting aspects of these relevant biological interactions.

Quorum sensing and indole-3-acetic acid degradation play a role in colonization and plant growth promotion of Arabidopsis thaliana by Burkholderia phytofirmans PsJN.

Although not fully understood, molecular communication in the rhizosphere plays an important role regulating traits involved in plant-bacteria association. Burkholderia phytofirmans PsJN is a well-known plant-growth-promoting bacterium, which establishes rhizospheric and endophytic colonization in different plants. A competent colonization is essential for plant-growth-promoting effects produced by bacteria. Using appropriate mutant strains of B. phytofirmans, we obtained evidence for the importance of N-acyl homoserine lactone-mediated (quorum sensing) cell-to-cell communication in efficient colonization of Arabidopsis thaliana plants and the establishment of a beneficial interaction. We also observed that bacterial degradation of the auxin indole-3-acetic acid (IAA) plays a key role in plant-growth-promoting traits and is necessary for efficient rhizosphere colonization. Wildtype B. phytofirmans but not the iacC mutant in IAA mineralization is able to restore promotion effects in roots of A. thaliana in the presence of exogenously added IAA, indicating the importance of this trait for promoting primary root length. Using a transgenic A. thaliana line with suppressed auxin signaling (miR393) and analyzing the expression of auxin receptors in wild-type inoculated plants, we provide evidence that auxin signaling in plants is necessary for the growth promotion effects produced by B. phytofirmans. The interplay between ethylene and auxin signaling was also confirmed by the response of the plant to a 1-aminocyclopropane-1-carboxylate deaminase bacterial mutant strain.

Factores de riesgo que influyen para el embarazo en adolescentes. Centro de Salud Monzón. Distrito de Monzón-Huánuco - 2006 / Risk factors affecting for pregnancy in adolescents. Health Center Monzon. District of Monzon-Huanuco-2006

A nivel mundial el embarazo precoz en adolescentes, constituye un problema de salud pública porque se advierten mayores complicaciones y un índice alto de mortalidad. Es por ello que el presente estudio: "Factores de riesgo que influyen para el embarazo en adolescentes en el Centro de Salud de Monzón- Distrito de Monzón. Noviembre-Diciembre 2006", tuvo como objetivo general: Determinar los factores de riesgo que influyen para el embarazo en adolescentes y como objetivos específicos: Identificar factores de riesgo socioeconómicos para el embarazo en adolescentes. Identificar factores de riesgo psicológicos para el embarazo en adolescentes e identificar factores de riesgo en salud Reproductiva para el embarazo en adolescentes. Se utilizó el Método Descriptivo de corte transversal. El instrumento utilizado fue un formulario tipo cuestionario conformado por preguntas de opción múltiple y opción binaria y como técnica la entrevista. La población estuvo conformada por 40 adolescentes embarazadas, que asistieron al centro de salud para control de embarazo. Dentro de las conclusiones tenemos; que Existe un porcentaje significativo del 22.5 por ciento de las adolescentes embarazadas con factores de riesgo alto, relacionadas a la frecuencia de discusiones en casa llegando al insulto y a la agresión física, agregado a ello están los problemas económicos, baja resiliencia, inicio precoz de las relaciones amorosas e inicio de las relaciones sexuales. Un porcentaje predominante del 57.5 por ciento con factores de riesgo bajo relacionadas a la comunicación con los padres, y la no convivencia de los mismos. Y un porcentaje menor del 20 por ciento de adolescentes embarazadas no presentan factor de riesgo. En relación al factor socioeconómico el 62.55 por ciento de las Adolescentes embarazadas presentan un riesgo bajo relacionados al hacinamiento, comunicación, convivencia de los padres y actitud frente a las discusiones de los padres, se evidencia un porcentaje significativo...

At world-wide level the precocious pregnancy in adolescents, constitutes a problem of public health because greater complications are noticed and a high index of mortality. It is for that reason that the present study: "Factors of risk that influence in center for the pregnancy in Adolescents of Health of Monsoon-District of Monsoon. November-December 2006", had like general mission: To determine the risk factors that influence for the pregnancy in adolescents and like specific objectives: To identify socioeconomic factors of risk for the pregnancy in adolescents. To identify psychological factors of risk for the pregnancy in adolescents and of identifying factors of risk in sexual or reproductive health for the pregnancy in adolescents. For it, the Descriptive Method of cross section was used. The used instrument was a form type questionnaire conformed by questions of multiple option and binary option and like technique the interview. The population was conformed by 40 pregnant adolescents, who attended the center of health for pregnancy control. Within the conclusions we have; that: There's a significant percentage of the 22.5 per cent of the adolescents embarrassed with factors of high risk, related to the frequency of discussions in house arriving at the insult and the physical aggression, aggregate to it is the economic problems, low resilience, precocious beginning of the loving relations and beginning of the sexual relations. A predominant percentage of the 57.5 per cent with factors of risk under related to the communication to the parents, and the no coexistence of such. And a smaller percentage of 20 per cent of pregnant adolescents does not present risk factor. In relation to the socioeconomic factor 62.55 per cent of related the pregnant adolescents present a risk under to the communication and coexistence of the parents and attitude as opposed to the discussions of the parents, demonstrates a significant percentage of 15 per cent of pregnant...