1.
J Org Chem
; 82(17): 9119-9125, 2017 09 01.
Article
in English
| MEDLINE
| ID: mdl-28795810
ABSTRACT
A concise and flexible synthesis of α,ß-unsaturated amidines via gold-catalyzed intermolecular ynamide amination/carbene 1,2-shift between ynamides and benzylic azides has been developed. Under mild reaction conditions, various α,ß-unsaturated amidines were obtained in mostly good yields, thus providing an efficient and atom-economic way for the construction of valuable α,ß-unsaturated amidines.