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1.
IEEE J Biomed Health Inform ; 26(6): 2693-2702, 2022 06.
Article in English | MEDLINE | ID: mdl-34928808

ABSTRACT

Cervical nucleus segmentation is a crucial and challenging issue in automatic pathological diagnosis due to uneven staining, blurry boundaries, and adherent or overlapping nuclei in nucleus images. To overcome the limitation of current methods, we propose a multi-task network based on U-Net for cervical nucleus segmentation. This network consists of a primary task and an auxiliary task. The primary task is employed to predict nuclei regions. The auxiliary task, which predicts the boundaries of nuclei, is designed to improve the feature extraction of the main task. Furthermore, a context encoding layer is added behind each encoding layer of the U-Net. The output of each context encoding layer is processed by an attention learning module and then fused with the features of the decoding layer. In addition, a codec block is used in the attention learning module to obtain saliency-based attention and focused attention simultaneously. Experiment results show that the proposed network performs better than the state-of-the-art methods on the 2014 ISBI dataset, BNS, MoNuSeg, and our nucluesSeg dataset.


Subject(s)
Image Processing, Computer-Assisted , Neural Networks, Computer , Attention , Cell Nucleus , Cervix Uteri , Female , Humans , Image Processing, Computer-Assisted/methods
2.
IEEE Trans Image Process ; 30: 4828-4839, 2021.
Article in English | MEDLINE | ID: mdl-33945477

ABSTRACT

Raindrops adhered to a glass window or camera lens appear in various blurring degrees and resolutions due to the difference in the degrees of raindrops aggregation. The removal of raindrops from a rainy image remains a challenging task because of the density and diversity of raindrops. The abundant location and blur level information are strong prior guide to the task of raindrop removal. However, existing methods use a binary mask to locate and estimate the raindrop with the value 1 (adhesion of raindrops) and 0 (no adhesion), which ignores the diversity of raindrops. Meanwhile, it is noticed that different scale versions of a rainy image have similar raindrop patterns, which makes it possible to employ such complementary information to represent raindrops. In this work, we first propose a soft mask with the value in [-1,1] indicating the blurring level of the raindrops on the background, and explore the positive effect of the blur degree attribute of raindrops on the task of raindrop removal. Secondly, we explore the multi-scale fusion representation for raindrops based on the deep features of the input multi-scale images. The framework is termed uncertainty guided multi-scale attention network (UMAN). Specifically, we construct a multi-scale pyramid structure and introduce an iterative mechanism to extract blur-level information about raindrops to guide the removal of raindrops at different scales. We further introduce the attention mechanism to fuse the input image with the blur-level information, which will highlight raindrop information and reduce the effects of redundant noise. Our proposed method is extensively evaluated on several benchmark datasets and obtains convincing results.

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