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J Med Virol ; 83(3): 496-500, 2011 Mar.
Article in English | MEDLINE | ID: mdl-21264871

ABSTRACT

Hantaviruses in Europe cause human hemorrhagic fever with renal syndrome (HFRS) with various degree of severity. The most severe form is caused by the Dobrava/Belgrade virus (DOBV), associated with the rodent Apodemus flavicollis. During the last decade cases of infection caused by DOBV have been reported in Central Europe. The present study is a report on two Czech patients with severe HFRS who were infected during their stay in a mountain hut in Northern Slovakia. The two patients, combined with a third case observed in the same year in a nearby village in the Czech Republic, suggest that this region in Central Europe has to be considered as endemic for HFRS.


Subject(s)
Hemorrhagic Fever with Renal Syndrome/diagnosis , Hemorrhagic Fever with Renal Syndrome/therapy , Orthohantavirus/physiology , Travel , Adult , Antibodies, Viral/blood , Czech Republic , Genes, Viral , Orthohantavirus/classification , Orthohantavirus/genetics , Hemorrhagic Fever with Renal Syndrome/genetics , Hemorrhagic Fever with Renal Syndrome/immunology , Humans , Male , Molecular Typing , Phylogeny , Slovakia , Treatment Outcome
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