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1.

[Synthesis and pharmacological properties of cis-3,10b-dimethyl-9-hydroxy-1,2,3,4,4a,5,6,10b-octahydrobenzol[f]isoquinoline (author's transl)]. / Synthese und pharmakologische Prüfung von cis-3,10b-Dimethyl-9-hydroxy-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]isochinolin.

Hahne, F; Zymalkowski, F; Braun, U.

Arch Pharm (Weinheim) ; 314(3): 197-204, 1981 Mar.

Article in German | MEDLINE | ID: mdl-7224830

Subject(s)

Analgesics/chemical synthesis , Isoquinolines/chemical synthesis , Animals , Isoquinolines/pharmacology , Male , Mice , Molecular Conformation

2.

[Structure dependance of antiplasmodic activity of 3-[N-(4-amidosulfonylphenyl)aminomethyl]-quinoline (author's transl)]. / Strukturabhängigkeit der antiplasmodischen Wirkung von 3-[N-(4'-Amidosulfonyl)-phenyl]-aminomethyl-chinolin.

Gaedcke, F; Knorr, R; Zymalkowski, F.

Arch Pharm (Weinheim) ; 313(2): 166-73, 1980 Feb.

Article in German | MEDLINE | ID: mdl-6989342

Subject(s)

Antimalarials/pharmacology , Quinolines/pharmacology , Sulfanilamides/pharmacology , Animals , Plasmodium berghei , Structure-Activity Relationship

3.

[Synthesis of quinolines with heterocyclic substituents at position 3 (author's transl)]. / Zur Synthese heterocyclisch substituierter Chinolin-3-Derivate.

Gaedcke, F; Zymalkowski, F.

Arch Pharm (Weinheim) ; 312(10): 812-5, 1979 Oct.

Article in German | MEDLINE | ID: mdl-396909

Subject(s)

Antimalarials/chemical synthesis , Quinolines/chemical synthesis , Animals , Plasmodium berghei/drug effects , Quinolines/pharmacology

4.

[Synthesis of 1-(3-quinolino)-2-alkylaminoethanols (author's transl)]. / Zur Synthese von 1-(3'-Chinolino)-2-alkylamino-ethanolen.

Gaedcke, F; Zymalkowski, F.

Arch Pharm (Weinheim) ; 312(9): 767-71, 1979 Sep.

Article in German | MEDLINE | ID: mdl-389197

Subject(s)

Antimalarials/chemical synthesis , Ethanolamines/chemical synthesis , Ethanolamines/pharmacology , Microbial Sensitivity Tests , Plasmodium berghei/drug effects

5.

[Synthesis of partially hydrogenated benzo(f)isoquinolines as potential analgetics (author's transl)]. / Die Synthese partiell hydrierter Benzo[f]isochinoline als potentielle Analgetika.

Hahne, F; Zymalkowski, F.

Arch Pharm (Weinheim) ; 312(6): 472-7, 1979 Jun.

Article in German | MEDLINE | ID: mdl-485784

Subject(s)

Analgesics/chemical synthesis , Isoquinolines/chemical synthesis , Animals , Isoquinolines/pharmacology

6.

Selective demethylation of polymethoxyxanthones with aqueous piperidine.

Chaudhuri, R K; Zymalkowski, F; Ghosal, S.

J Pharm Sci ; 67(9): 1321-2, 1978 Sep.

Article in English | MEDLINE | ID: mdl-690843

ABSTRACT

Data are presented for selective demethylation of eight polymethoxyxanthones with aqueous piperdine. Clarification and rationalization of the present and previous observations are made. The mechanism is defined in terms of both resonance effects and steric factors.

Subject(s)

Piperidines , Xanthenes , Chemical Phenomena , Chemistry , Dealkylation

7.

[Constituents of Cassia siamea (author's transl)]. / Inhaltsstoffe von Cassia siamea.

Ahn, B Z; Degen, U; Lienjayetz, C; Pachaly, P; Zymalkowski, F.

Arch Pharm (Weinheim) ; 311(7): 569-78, 1978 Jul.

Article in German | MEDLINE | ID: mdl-678066

Subject(s)

Cassia/analysis , Plants, Medicinal/analysis , Chemical Phenomena , Chemistry

8.

Quantitative structure activity correlation of anti-Aspergillus niger activity of 4-substituted benzophenones.

Chaudhuri, R K; Zymalkowski, F; Wiedemann, B; Ghosal, S.

Pharm Acta Helv ; 53(7): 205-6, 1978.

Article in English | MEDLINE | ID: mdl-733822

Subject(s)

Aspergillus niger/drug effects , Benzophenones/pharmacology , Structure-Activity Relationship

9.

[N-substituted beta-phenylserinehitriles from mandelaldehyde]. / N-Substituierte beta-Phenylserinnitrile aus Mandelaldehyd.

Lehmann, J; Tinapp, P; Zymalkowski, F.

Arch Pharm (Weinheim) ; 310(6): 524-7, 1977 Jun.

Article in German | MEDLINE | ID: mdl-883886

Subject(s)

Aldehydes , Mandelic Acids , Serine/analogs & derivatives , Nitriles/chemical synthesis , Serine/chemical synthesis

10.

[Isolation and structural elucidation of quaternary tetrahydroberine alkaloids (author's transl)]. / Alkaloide aus der thailändischen Menispermaceen-Droge Krung Kha Mao (Cyclea barbata), 6. Mitt. Isolierung und Strukturaufklärung quartärer Tetrahydroprotoberberin-Alkaloide

Martin, H J; Pachaly, P; Zymalkowski, F.

Arch Pharm (Weinheim) ; 26(4): 314-9, 1977 Apr.

Article in German | MEDLINE | ID: mdl-860900

Subject(s)

Berberine Alkaloids/isolation & purification , Plants, Medicinal/analysis , Chemical Phenomena , Chemistry , Methylation , Spectrophotometry, Infrared , Thailand

11.

[Alkaloids from the Thai drug "krung kha mao" (cyclea barbata, menispermaceae), V: isolation and structural elucidation of further bisbenzylisoquinoline alkaloids (author's transl)]. / Alkaloide aus der thailändischen Menispermaceen-Droge Krung Kha Mao (Cyclea barbata), 5. Mitt. Isolierung und Strukturaufklärung weiterer Bisbenzylisochinolin-Alkaloide

Dahmen, K; Pachaly, P; Zymalkowski, F.

Arch Pharm (Weinheim) ; 310(2): 95-102, 1977 Feb.

Article in German | MEDLINE | ID: mdl-849127

Subject(s)

Isoquinolines/analysis , Plant Extracts/analysis , Chemical Phenomena , Chemistry , Thailand

12.

[Sulphur containing heterocycles from benzothienylethylamine (author's transl)]. / Schwefelhaltige Heterocyclen aus Benzothienyläthylamin

Wolf, G; Zymalkowski, F.

Arch Pharm (Weinheim) ; 309(4): 279-88, 1976 Apr.

Article in German | MEDLINE | ID: mdl-962534

Subject(s)

Heterocyclic Compounds/chemical synthesis , Cyclization , Methods , Sulfur

13.

[The aminolysis of beta-phenylglycide esters. 3. Chemical structure proof]. / Zur Aminolyse von beta-Phenylglycidestern, 3. Mitt

Lehmann, J; Zymalkowski, F.

Arch Pharm (Weinheim) ; 309(5): 427-9, 1976.

Article in German | MEDLINE | ID: mdl-962554

Subject(s)

Amino Acids , Chemical Phenomena , Chemistry , Esters

14.

[Synthesis of quinoline-3- and quinoxaline-2- derivatives and their actions against various malarial parasites]. / Synthese von Chinolin-3- und Chinoxalin-2-derivaten sowie ihre Wirkung gegen verschiedene Malariaerreger

Djudovic, P; Maier, W; Piekarski, G; Schornstein, U; Zymalkowski, F.

Pharmazie ; 31(12): 845-9, 1976.

Article in German | MEDLINE | ID: mdl-799316

Subject(s)

Malaria/drug therapy , Quinolines , Quinoxalines , Animals , Chemical Phenomena , Chemistry , Drug Resistance, Microbial , Mice , Plasmodium/drug effects , Plasmodium berghei/drug effects , Quinolines/chemical synthesis , Quinolines/therapeutic use , Quinoxalines/chemical synthesis , Quinoxalines/therapeutic use

15.

[Synthesis and reactivity of some alpha-bromoketals (author's transl)]. / Herstellung und reaktives Verhalten einiger alpha-Bromketale

Kahlert, E U; Zymalkowski, F.

Arch Pharm (Weinheim) ; 308(12): 946-50, 1975 Dec.

Article in German | MEDLINE | ID: mdl-1221975

Subject(s)

Dioxolanes/chemical synthesis , Dioxoles/chemical synthesis , Bromine , Methods

16.

[Stereoselective syntheses of the diasteromeric D,L-3-(p-fluorophenyl)-serines and -isoserines (author's transl)]. / Stereoselektive Synthesen der diastereomeren D,L-3-(p-Fluorphenyl)-serine und -isoserine

Blazevic, N; Zymalkowski, F.

Arch Pharm (Weinheim) ; 308(7): 541-9, 1975 Jul.

Article in German | MEDLINE | ID: mdl-1164175

Subject(s)

Serine/analogs & derivatives , Fluorobenzenes/chemical synthesis , Serine/chemical synthesis , Stereoisomerism

17.

[Synthesis of beta-phenyl-isoserines by ammonolysis of beta-phenylglycidates, I. (author's transl)]. / Die Synthese von beta-Phenyl-isoserinen durch Ammonolyse von beta-Phenyl-glycidestern, I

Kamandi, E; Frahm, A W; Zymalkowski, F.

Arch Pharm (Weinheim) ; 307(11): 871-8, 1974 Nov.

Article in German | MEDLINE | ID: mdl-4433222

Subject(s)

Epoxy Compounds , Ethers, Cyclic , Phenylpropionates , Serine/analogs & derivatives , Hydrolysis , Isomerism , Magnetic Resonance Spectroscopy , Serine/chemical synthesis

18.

[Gamma-pyridyl- and gamma-quinolyl-butyrolactones as potential antihelminthics (author's transl)]. / Gamma-Pyridyl- und gamma-Chinolyl-butyrolactone als potentielle Antihelminthika

Michel, H; Zymalkowski, F.

Arch Pharm (Weinheim) ; 307(9): 689-94, 1974 Sep.

Article in German | MEDLINE | ID: mdl-4422022

Subject(s)

Anthelmintics/chemical synthesis , Lactones/chemical synthesis , Butyrates/chemical synthesis , Pyridines/chemical synthesis , Quinolines/chemical synthesis

19.

[Synthesis of 1-aza-desaza-berbine (author's transl)]. / Eine Synthese des 1-Aza-des-N-berbins

Klar, H; Zymalkowski, F.

Arch Pharm (Weinheim) ; 307(8): 577-84, 1974 Aug.

Article in German | MEDLINE | ID: mdl-4849858

Subject(s)

Aza Compounds/chemical synthesis , Berberine Alkaloids/chemical synthesis , Chemical Phenomena , Chemistry , Structure-Activity Relationship

20.

[Alkaloids from menispermaceae drugs from Thailand. IV. Isolation and structure of two berbamine alkaloids (author's transl)]. / Alkaloide aus der thailändischen Menispermaceendroge Krung Kha Mao (Cyclea barbata). 4. Isolierung und Strukturaufklärung zweir Berbamin-Alkaloide

Goepel, C; Yupraphat, T; Pachaly, P; Zymalkowski, F.

Planta Med ; 26(1): 94-7, 1974 Aug.

Article in German | MEDLINE | ID: mdl-4848009

Subject(s)

Alkaloids/isolation & purification , Plants, Medicinal/analysis , Alkaloids/analysis , Quinolines/isolation & purification , Thailand

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