[The combined action of ionizing radiation and nitro compounds on the activity of the basic enzymes of glutamic acid metabolism]. / Sochetannoe vozdeistvie ioniziruiushchego izlucheniia i nitrosoedinenii na aktivnost' osnovnykh fermentov obmena glutaminovoi kisloty.

The activity of aspartate aminotransferase, glutamate dehydrogenase in the liver of rats in 1, 7 and 15 days after gamma irradiation effect of the dose of 0.5 Gy on the background of consumption by animals of sodium nitrate, sodium nitrite and nitrosodiethylamine was studied. The combined influence of chemical agents and gamma irradiation modified the effects of nitro compounds-xenobiotics on processes of the synthesis and dissociation of the glutamic acid as well as the intensity of transamination of the reamination by aspartate aminotransferase.

[Indicators of lipid peroxidation in rat liver mitochondria after exposing them to some xenobiotics and the action of low dose radiation]. / Pokazateli peroksidnogo okisleniia lipidov v titokhondriiakh pecheni krys posle vvedeniia im nekotorykh ksenobiotikov i deistviia radiatsii v maloi doze.

The contents of primary and secondary products of lipid peroxidation in rat liver mitochondria through 1, 7 and 15 days after gamma-irradiation in a dose 0.5 Gy on a background of consumption of sodium nitrate, sodium nitrite and nitrosodiethylamine was investigated. Is was shown, that gamma-irradiation on a background of sodium nitrate, sodium nitrite and nitrosodiethylamine modified effects of nitrocompounds on speed of lipid peroxidation. Besides, combine action of sodium nitrate and gamma-irradiation has more effect in comparison with influencing of separate factors. The observed changes in quantity of lipid peroxidation products are rather stable and are kept during all terms of supervision.

[Effect of low-energy laser radiation on lipid peroxidation intensity]. / Vliianie nizkoénergeticheskogo lazernogo izlucheniia na intensivnost' perekisnogo okisleniia lipidov.

Local effect of low-energy laser radiation was shown to alter the rate of lipid peroxidation in rat liver tissue which was manifested as a weak accumulation of primary and secondary lipid peroxidation products. The laser radiation effect proved to be generalized as the content of lipid peroxidation products was similarly altered both in liver tissue and in blood regardless of the radiation site.

[Aspartate aminotransferase and glutamate dehydrogenase activity in the rat brain during infrared laser exposure]. / Aktivnost' aspertataminotransferazy i glutamatdegidrogenazy v golovnom mozge krys pri infrakrasnom lazernom vozdeistvii.

In experiments in vivo it was shown that upon low-intensity infrared irradiation changes in the activity of main enzymes of glutamic acid metabolism are a function of time of exposure and flux density.

[Modification with dyes of the effects of laser irradiation on various enzymes of glutamic acid metabolism]. / Modifikatsiia krasiteliami éffektov lazernogo vozdeistviia na nekotorye fermenty obmena glutaminovoi kisloty.

In the in vivo experiments it has been shown that a mixture of low-intensity helium-neon laser radiation and dyes modifies the effect of laser radiation on the activity of basic enzymes of glutamic acid metabolism.

[Catecholamine content and acetylcholinesterase activity in the brain of rats exposed to lasers]. / Soderzhanie katekholaminov i aktivnost' atsetilkholinésterazy v golovnom mozge krys pri lazernom vozdeistvii.

The catecholamine content was quantitated and acetylcholinesterase activity determined in rat brain locally exposed to laser radiation. It was shown that the adrenaline/noradrenaline ratio changed in the tissues under study and the cholinergic system was involved in the abscopal effect of laser radiation.

[Effect of continuous and modulated laser radiation on the activity of enzymes of glutamic acid metabolism in rat tissues]. / Vliianie nepreryvnogo i modulirovannogo lazernogo izlucheniia na aktivnost' fermentov obmena glutaminovoi kisloty v tkaniakh krys.

A comparative study was made of the effect of continuous and modulated laser radiation on activity of aspartate aminotransferase and glutamate dehydrogenase in the brain and liver of rats. The impulse laser radiation has proved to be most effective with respect to the parameters under study at modulation frequencies of 10 and 50 Hz.

[Changes in carbohydrate-energy metabolism in the rat brain during laser irradiation]. / Izmeneniiaa uglevodno-énergeticheskogo obmena v golovnom mozge krys pri lazernom obluchenii.

Laser irradiation of rats increases the activity of hexokinase and aerobic isoenzymes of lactate dehydrogenase, activates succinate- and alpha-oxoglutarate dehydrogenase and decreases the level of amino acids of a glutamine group.

[Effect of local laser irradiation on the activity of enzymes of glutamic acid metabolism in rat tissues]. / Vliianie lokal'nogo lazernogo oblucheniia na aktivnost' nekotorykh fermentov obmena glutaminovoi kisloty v tkaniakh krys.

In experiments in vivo it was shown that local laser irradiation of the parietal region of the rat head changed the activity of principal enzymes of glutamic acid metabolism both in the brain and in the liver, whereas peripheral irradiation of epigastric region caused changes in the activity of the studied enzymes in the affected site only.

[Enzyme activity of glutamic acid metabolism and the Krebs cycle in the brain of rats laser-irradiated against a background of altered adrenoreceptor function]. / Aktivnost' nekotorykh fermentov obmena glutaminovoi kisloty i tsikla Krebsa v golovnom mozge krys pri lazernom obluchenii na fone izmenennogo funktsional'nogo sostoianiia adrenoretseptorov.

In the in vivo experiments it was demonstrated that the effect of a helium-neon laser (lambda = 632.8 nm), at the background of altered functional status of adrenoreceptors, changes the activity of some enzymes of the glutamic acid metabolism and the Krebs cycle. This may be attributed to both the direct effect of laser radiation and the indirect effect via the adrenergic system.