[Electron microscopy and histochemical study of the neural apparatus of the heart in experimental myocardial infarct]. / Elektronno-mikroskopicheskoe i gistokhimicheskoe izuchenie nervnogo apparata serdtsa pri éksperimental'nom infarkte miokarda.

Electron microscopic study of intraorgan nervous ganglia and histochemical investigation of adrenergic innervation of rabbit heart in experimental myocardial infarction has been carried out. Changes in ganglia are shown to develop first of all in neuron bodies. Disturbances in ultrastructure of synaptic contacts are, as a rule, found from the third day of myocardial infarction. The amount of mediator in adrenergic terminalia is being reduced and there is a change in its distribution along the nerve fibers not only in the zone of the myocardial infarction but also in the zones beyond infarction. Intravenous infusion of nitroglycerin favours a retaining of the mediator in the neuronal depot.

[Testosterone content in the blood plasma in acute myocardial infarct]. / Soderzhanie testosterona v plazme krovi bol'nykh ostrym infarktom miokarda.

The testosterone content was studied in 50 male patients, who sustained myocardial infarction, on the 1,3--5,10 and 20th day of the disease. Forty seven patients with ischemic heart disease served as controls. The results obtained were analysed in relation to the patients age and the course type of the disease. The testosterone concentration on the 1st day of myocardial infarction was not different from that in the ischemic heart disease patients. Elevation of the testosterone level was observed in the myocardial infarction patients during the acute period of the disease, but its dynamics depended on the course type of the disease. No relationship was revealed between the testosterone level increase and the patients age.

[Certain humoral factors in acute myocardial infarct complicated by cardiogenic shock]. / Nekotorye gumoral'nye faktory v ostrom periode infarkta miokarda, oslozhnennogo kardiogennym shokom

The activity of the sympathoadrenal and renin-angiotensin-aldosterone systems was studied in patients with myocardial infarction complicated by cardiogenic shock. During the initial 12 hours after the onset of myocardial infarction an increased plasma level of adrenalin and noradrenal is observed, which then returns to the normal level on the 3rd day. In cases of cardiogenic shock a lower content of catecholamines in blood is noted. The determinations of renin activity in the plasma of peripheral venous blood demonstrated that it was increased since the 1st day of the disease in the myocardial infarction patients, but that its maximum elevation fell within the 7th--10th days. In patients with cardiogenic shock the plasma renin activity was much higher than in those with uncomplicated myocardial infarction. Urine aldosterone excretion was higher in patients with cardiogenick shock since the 1st day of the disease than in those with an uncomplicated course of myocardial infarction. The study of the electrolyte balance in patients with myocardial infarction complicated by cardiogenic shock demonstrated that on the 1st day of the disease the potassium level in plasma and erythrocytes was decreased, while the sodium concentration was somewhat increased.