Subject(s)
Estrogens/pharmacology , Muscles/drug effects , Animals , Female , Mice , Myometrium/drug effects , Sexual Maturation , Uterus/drug effectsABSTRACT
Ascorbic acid (vitamin C) was given to 144-days-old layer chickens mixed with their ration at three concentrations: 30, 60 and 90 p.p.m. for 6 months. Cholesterol levels in blood serum (CS) and egg yolk (CE) were measured every 6 weeks (four periods); there was a marked decrease in CS in most treated birds, especially those receiving the highest concentration of vitamin C. There was also a slight decrease in CE in most treated birds. Thyroidal weight showed a significant increase in most treated groups, especially those receiving the highest concentration of vitamin C.
Subject(s)
Ascorbic Acid/pharmacology , Chickens/metabolism , Cholesterol/metabolism , Egg Yolk/analysis , Animals , Body Weight/drug effects , Chickens/blood , Cholesterol/blood , Female , Organ Size/drug effects , Thyroid Gland/anatomy & histologySubject(s)
Oxytocin/pharmacology , Spermatogenesis/drug effects , Testis/physiology , Animals , Male , Mice , Sexual Maturation , Testis/cytology , Testis/drug effectsABSTRACT
The effects of oxytocin on ovarian function have been studied in immature rats of 25 days of age. The hormone was injected subcutaneously daily for 5 days in two doses: 50 and 250 millimicrons per animal, to intact females, hysterectomized or injected simultaneously with indomethacin (2 mg/kg). Ovarian and uterine weights increased in all treated animals. Plasma estradiol 17 beta levels increased, while plasma progesterone level did not change. The relevance of this study was to precise the trophic role of oxytocin on ovary and uterus. The changes observed did not seem to be associated with prostaglandin E secretion.
