[Role of the interferon system in the course of neglected forms of colorectal cancer]. / Rol' interferonovoi sistemy v techenii zapushchennykh form kolorektal'nogo raka.

Operations for neglected forms of colorectal carcinoma were performed on 66 patients. The interferon status was determined before the operation, on the 1st, 7th and 14th days after the operative intervention. "Viferon-2" was given to 18 patients (starting from 2 days before the operation) with the daily dose 1,000,000 IU. The investigation has shown that deep inhibition of production of interferon (alpha and beta by leukocytes increased risk of the development of postoperative pyo-inflammatory complications. Using the preparation "Viferon-2" is highly effective for prevention of such complications.

[Cycloferon in treating duodenal ulcers in rats]. / Tsikloferon v terapii iazvy dvenadtsatiperstnoi kishki u krys.

The possibility of using cycloferon (interferon inductor) for a complex treatment (in combination with the main drug solcoseryl possessing pronounced therapeutic properties) of duodenum ulcers was experimentally studied in male rats. The experiments showed a considerable difference in the interferon status of animals with model duodenum ulcers treated with cycloferon, solcoseryl, their combination, and placebo (control). The healing effect of solcoseryl administered in combination with cycloferon exceeded that of each component administered separately.