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1.
An Acad Bras Cienc ; 87(3): 1653-74, 2015 Sep.
Article in English | MEDLINE | ID: mdl-26312421

ABSTRACT

The air transportation network in a country has a great impact on the local, national and global economy. In this paper, we analyze the air transportation network in Brazil with complex network features to better understand its characteristics. In our analysis, we built networks composed either by national or by international flights. We also consider the network when both types of flights are put together. Interesting conclusions emerge from our analysis. For instance, Viracopos Airport (Campinas City) is the most central and connected airport on the national flights network. Any operational problem in this airport separates the Brazilian national network into six distinct subnetworks. Moreover, the Brazilian air transportation network exhibits small world characteristics and national connections network follows a power law distribution. Therefore, our analysis sheds light on the current Brazilian air transportation infrastructure, bringing a novel understanding that may help face the recent fast growth in the usage of the Brazilian transport network.

2.
IEEE Trans Biomed Eng ; 62(2): 600-8, 2015 Feb.
Article in English | MEDLINE | ID: mdl-25296402

ABSTRACT

This paper compares different numerical methods for the solution of myocyte models of cardiac electrophysiology. In particular, it presents how the technique called uniformization method substantially increases the stability of simple first-order methods such as Euler explicit method and Rush-Larsen (RL) method, for the solution of modern electrophysiology models that are based on continuous-time Markov chains (MCs) for the description of subcellular structures, such as ion channels. The MCs are often associated with stiff ordinary differential equations that severely limit the time step used by these traditional methods. By using the uniformization method, we could significantly increase the time steps for the solution of different cardiac electrophysiology models and improve the computational performance up to 150 times compared to the performance of Euler's and RL's methods.


Subject(s)
Action Potentials/physiology , Heart Conduction System/physiology , Markov Chains , Models, Cardiovascular , Models, Statistical , Myocytes, Cardiac/physiology , Animals , Cells, Cultured , Computer Simulation , Humans
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