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Rhinovirus C and respiratory exacerbations in children with cystic fibrosis.

de Almeida, Marina B; Zerbinati, Rodrigo M; Tateno, Adriana F; Oliveira, Cristina M; Romão, Renata M; Rodrigues, Joaquim C; Pannuti, Cláudio S; da Silva Filho, Luiz Vicente F.

Emerg Infect Dis ; 16(6): 996-9, 2010 Jun.

Article in English | MEDLINE | ID: mdl-20507756

ABSTRACT

To investigate a possible role for human rhinovirus C in respiratory exacerbations of children with cystic fibrosis, we conducted microbiologic testing on respiratory specimens from 103 such patients in São Paulo, Brazil, during 2006-2007. A significant association was found between the presence of human rhinovirus C and respiratory exacerbations.

Subject(s)

Cystic Fibrosis/complications , Picornaviridae Infections/etiology , Respiratory Tract Infections/etiology , Rhinovirus/isolation & purification , Adolescent , Brazil/epidemiology , Child , Child, Preschool , Cystic Fibrosis/epidemiology , Female , Humans , Infant , Male , Molecular Sequence Data , Mucus/virology , Nasopharynx/virology , Phylogeny , Picornaviridae Infections/epidemiology , RNA, Viral/analysis , RNA, Viral/genetics , Respiratory Tract Infections/epidemiology , Rhinovirus/genetics , Sequence Analysis, RNA , Species Specificity , Sputum/virology

ABSTRACT

Subject(s)

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