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1.
An Bras Dermatol ; 88(6): 989-91, 2013.
Article in English | MEDLINE | ID: mdl-24474114

ABSTRACT

Dermatoscopy of melanocytic lesions has guided the decision of when or not to biopsy a lesion. The use of this tool has increased clinical examination's sensitivity and specificity in 89% and 96% respectively. However, dermatoscopic evaluation of amelanotic or hypomelanotic melanomas, as well as metastases, can be difficult. There is still no standardization for the analysis of these pathologies, which relies mostly on their vascular pattern. We describe the dermatoscopy of acral metastatic amelanotic melanoma.


Subject(s)
Melanoma, Amelanotic/pathology , Skin Neoplasms/pathology , Adult , Biopsy , Dermoscopy , Female , Humans , Sensitivity and Specificity
2.
Cutis ; 90(6): 285-8, 2012 Dec.
Article in English | MEDLINE | ID: mdl-23409476

ABSTRACT

Congenital dermatofibrosarcoma protuberans (DFSP) is a rare dermal and subcutaneous neoplasm of low-grade malignant behavior that is characterized by a low frequency of metastases with locally invasive growth. Its occurrence at birth and during childhood is rare. We present a case of a patient who was born with a light brown macule on his right buttock that was misdiagnosed as localized scleroderma. The lesion progressed into reddish atrophic plaques and nodules extending to the iliac region and the gluteal fold. At 5 years of age, a diagnosis of congenital DFSP was made based on clinical and immunohistochemical characteristics (CD34 positivity and spindle cell proliferation). Although there was a delay in diagnosis, a 3-step excision was proposed with a final step of Mohs micrographic surgery (MMS).


Subject(s)
Dermatofibrosarcoma/diagnosis , Diagnostic Errors , Skin Neoplasms/diagnosis , Child, Preschool , Dermatofibrosarcoma/congenital , Dermatofibrosarcoma/surgery , Humans , Immunohistochemistry , Male , Skin Neoplasms/congenital , Skin Neoplasms/surgery
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