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1.
Farm. comunitarios (Internet) ; 14(Supl 1): 1, junio 2022. ilus
Article in Spanish | IBECS | ID: ibc-209411

ABSTRACT

JUSTIFICACIÓN: la búsqueda de un estado y aspecto óptimo de salud, la prevención de enfermedades y el retraso del envejecimiento conlleva el consumo de complementos alimenticios entre otros productos de autocuidado. La comercialización de complementos alimenticios, distribuidos tradicionalmente en farmacias, se ha diversificado, si bien el canal farmacéutico se caracteriza por asegurar la calidad y seguridad que el consumidor exige y precisa, no solamente por la selección de productos que distribuye, sino por la dispensación informada que ofrece. Se sospecha que no todos los complementos alimenticios en el mercado cumplen con la normativa vigente y por ello el consumidor puede exponerse a situaciones de riesgo por desconocimiento. OBJETIVO: este estudio tiene por objeto la verificación de la adecuación a la norma del etiquetado de una selección de complementos alimenticios antienvejecimiento. Material y métodos Se han estudiado las menciones del etiquetado de los 27 complementos alimenticios antienvejecimiento más vendidos en la provincia de S/C de Tenerife, según el volumen de ventas en los dos almacenes mayoristas de medicamentos de Santa Cruz de Tenerife (COFARTE y COFARES). Se ha comprobado su adecuación a la normativa de aplicación; Real Decreto 1487/2009, relativo a los complementos alimenticios), Reglamento (CE) Nº 1170/2009 y Reglamento (UE) Nº 1169/2011. (AU)


Subject(s)
Humans , Disease Prevention , Health , Aging , Dietary Supplements , Pharmacies
2.
Euro Surveill ; 19(47): 20971, 2014 Nov 27.
Article in English | MEDLINE | ID: mdl-25443036

ABSTRACT

During 2000 to 2009, data on people undergoing HIV testing and on those newly diagnosed with HIV were collected in a network of 20 Spanish clinics specialising in sexually transmitted infections and/or HIV testing and counselling. The number of tests performed, overall and disaggregated by different variables, was obtained. HIV prevalence among first-time testers and HIV incidence among repeat testers were calculated. To evaluate trends, joinpoint regression models were fitted. In total, 236,939 HIV tests were performed for 165,745 individuals. Overall HIV prevalence among persons seeking HIV testing was 2.5% (95% CI: 2.4 to 2.6). Prevalence was highest in male sex workers who had sex with other men (19.0% (95% CI: 16.7 to 21.4)) and was lowest in female sex workers (0.8% (95% CI: 0.7 to 0.9)). Significant trends in prevalence were observed in men who have sex with men (MSM) (increasing) and heterosexual individuals (decreasing). The incidence analysis included 30,679 persons, 64,104 person-years (py) of follow-up and 642 seroconversions. The overall incidence rate (IR) was 1.0/100 py (95% CI: 0.9/100 to 1.1/100). Incidence was significantly higher in men and transgender females than in women (1.8/100 py (95% CI: 1.6 to 1.9), 1.2/100 py (95% CI: 0.5 to 2.8) and 0.1/100 py (95% CI: 0.09 to 0.2) respectively) and increased with age until 35­39 years. IRs in MSM and people who inject drugs were significantly greater than in heterosexual individuals (2.5/100 py (95% CI: 2.3 to 2.7), 1.6/100 py (95% CI: 1.1 to 2.2) and 0.1/100 py (95% CI: 0.09 to 0.2) respectively), and an upward trend was observed in MSM. Our results call for HIV prevention to be reinforced in MSM and transgender women in Spain.


Subject(s)
AIDS Serodiagnosis/statistics & numerical data , HIV Infections/epidemiology , HIV Seroprevalence/trends , Heterosexuality/statistics & numerical data , Homosexuality, Male/statistics & numerical data , Adolescent , Adult , Antiretroviral Therapy, Highly Active , Cohort Studies , Female , HIV Infections/diagnosis , HIV Infections/drug therapy , Humans , Incidence , Logistic Models , Male , Middle Aged , Prevalence , Sex Workers , Sexual Behavior , Sexually Transmitted Diseases/diagnosis , Sexually Transmitted Diseases/epidemiology , Spain/epidemiology , Substance Abuse, Intravenous , Transgender Persons , Vulnerable Populations , Young Adult
3.
Euro Surveill ; 14(48)2009 Dec 03.
Article in English | MEDLINE | ID: mdl-20003899

ABSTRACT

In Spain, neither the HIV nor the STI national surveillance systems collect information on HIV/STI co-infection. However, there are two networks based on HIV/STI clinics which gather this data. We describe HIV prevalence in men who have sex with men (MSM) diagnosed with infectious syphilis and/or gonorrhoea in 15 STI clinics; and concurrent diagnoses of STI in MSM newly diagnosed with HIV in 19 HIV/STI clinics. In total, 572 MSM were diagnosed with infectious syphilis and 580 with gonorrhoea during 2005-2007. HIV prevalence among syphilis and gonorrhoea cases was 29.8% and 15.2% respectively. In the multivariate analysis, HIV/syphilis co-infection was associated with being Latin American; having a history of STI; reporting exclusively anal intercourse; and having sex with casual or several types of partners. HIV and gonorrhoea co-infection was associated with age older than 45 years; having no education or only primary education completed; and having a history of STI. In total, 1,462 HIV infections were newly diagnosed among MSM during 2003-2007. Of these, 31.0% were diagnosed with other STI at the same time. Factors associated with STI co-infection among new HIV cases in MSM were being Latin American; and having sex with casual partners or with both steady and casual partners. In Spain, a considerable proportion of MSM are co-infected with HIV and STI.


Subject(s)
Disease Outbreaks/statistics & numerical data , HIV Infections/epidemiology , Homosexuality, Male/statistics & numerical data , Adult , Humans , Incidence , Male , Population Surveillance , Risk Assessment , Risk Factors , Spain/epidemiology
4.
Euro Surveill ; 9(5): 27-9, 2004 May.
Article in English | MEDLINE | ID: mdl-15208470

ABSTRACT

HIV infection in Spain was monitored in persons undergoing voluntary HIV testing in ten sentinel clinics between 1992 and 2002. Only patients on their first visit were considered for inclusion, and their numbers rose from 4426 in 1992 to 6649 in 2002. Most of them recognised their risk exposure as heterosexual. The proportion of injecting drug users decreased from 19% to 2% of the study population, and the proportion of female sex workers increased from 6% to 26%. The number of patients diagnosed with HIV infection declined from 604 in 1992 to 153 in 2002, and HIV prevalence fell from 13.6% to 2.3% in the same period. In all risk exposure categories, a decrease in HIV prevalence was observed, more pronounced during the first few years and stabilised in the later years. In 2002, the highest HIV prevalence was found in injecting drug users (IDUs) (14.2%), homo/bisexual men (7.5%) and individuals who had an HIV infected heterosexual partner (10.2%).


Subject(s)
HIV Infections/epidemiology , Sentinel Surveillance , Adult , Ambulatory Care Facilities , Female , HIV Seroprevalence/trends , Humans , Male , Prevalence , Sex Work/statistics & numerical data , Sexuality/statistics & numerical data , Spain/epidemiology , Substance Abuse, Intravenous/epidemiology
5.
Aten Primaria ; 33(9): 483-8, 2004 May 31.
Article in Spanish | MEDLINE | ID: mdl-15207145

ABSTRACT

OBJECTIVE: To describe the prevalence of HIV infection in persons tested between 1992 and 2001. DESIGN: Descriptive, cross-sectional epidemiological study. SETTING: 10 ambulatory centers specialized in diagnosing HIV, located in 9 cities in Spain. PARTICIPANTS: 53,183 persons older than 12 years, tested for the first time for HIV. MAIN MEASURES: Number of persons tested per year, number of persons diagnosed as seropositive for HIV according to sex, age group and category of exposure. RESULTS: The number of persons tested increased from 4401 in 1992 to 6407 in 2001. Approximately half reported heterosexual risk exposure/exposure through high-risk heterosexual behaviors, excluding prostitution. Intravenous drug users (IVDU) increased from 15.3% in 1992-1993 to 1.4% in 2000-2001, and women prostitutes/female sex workers increased from 6.7% to 25.1%. A total of 2898 persons were diagnosed as having HIV infection; 78% of them were men. The number of diagnoses decreased from a high of 1058 in 1992-1993 to 304 in 2000-2001, and this trend was seen for all categories of exposure except female prostitutes and men with heterosexual risk factors. The prevalence decreased from 14% in 1992 to 2% in 2001. There were decreases in all categories of exposure, especially during the first years of the study, with a tendency to level off. In 2001 the prevalence figures were 23.8% for IVDU, 7.9% for homosexual men and women, 0.8% for female sex workers and 1% for other heterosexual men and women. CONCLUSIONS: The specialized diagnostic centers play an important role in diagnosing HIV, and this service complements primary care services. Greater efforts are needed in the prevention of HIV infection.


Subject(s)
HIV Infections/epidemiology , Adult , Cross-Sectional Studies , Female , HIV Infections/diagnosis , Humans , Male , Middle Aged , Prevalence , Spain , Urban Health
6.
Euro Surveill ; 9(5): 3-4, 2004 May.
Article in English | MEDLINE | ID: mdl-29183455

ABSTRACT

HIV infection in Spain was monitored in persons undergoing voluntary HIV testing in ten sentinel clinics between 1992 and 2002. Only patients on their first visit were considered for inclusion, and their numbers rose from 4426 in 1992 to 6649 in 2002. Most of them recognised their risk exposure as heterosexual. The proportion of injecting drug users decreased from 19% to 2% of the study population, and the proportion of female sex workers increased from 6% to 26%. The number of patients diagnosed with HIV infection declined from 604 in 1992 to 153 in 2002, and HIV prevalence fell from 13.6% to 2.3% in the same period. In all risk exposure categories, a decrease in HIV prevalence was observed, more pronounced during the first few years and stabilised in the later years. In 2002, the highest HIV prevalence was found in injecting drug users (IDUs) (14.2%), homo/bisexual men (7.5%) and individuals who had an HIV infected heterosexual partner (10.2%).

7.
Vaccine ; 16(4): 366-73, 1998 Feb.
Article in English | MEDLINE | ID: mdl-9607057

ABSTRACT

The control of tick infestations and the transmission of tick-borne diseases remains a challenge for the cattle industry in tropical and subtropical areas of the world. Traditional control methods have been only partially successful and the parasites continue to result in significant losses for the cattle industry. Recently, vaccines containing the recombinant Boophilus microplus gut antigen Bm86 have been developed. These vaccines have been shown to control tick infestations in the field. However, extensive field studies investigating the efficacy and cost-effectiveness of vaccination have not been reported and are needed to appraise the effect of this new approach for tick control. Here is reported the results of the application of Gavac in a field trial including more than 260,000 animals in Cuba. In this study the correlation between the antibody response to vaccination and the effect on ticks fertility is determined. Physiological status of the animals was found to affect the primary response to vaccination but not the antibody titers after revaccination. A cost-effectiveness analysis showed a 60% reduction in the number acaricide treatments, together with the control of tick infestations and transmission of babesiosis, which resulted in savings of $23.4 animal-1 year-1. These results clearly demonstrate the advantage of vaccination and support the application of Gavac for tick control.


Subject(s)
Cattle Diseases/economics , Membrane Glycoproteins/immunology , Recombinant Proteins , Tick Infestations/veterinary , Ticks/immunology , Vaccines/economics , Vaccines/immunology , Animals , Cattle , Cattle Diseases/prevention & control , Cost-Benefit Analysis , Cuba , Female , Tick Infestations/prevention & control , Vaccines/administration & dosage , Vaccines, Synthetic/immunology
8.
Arzneimittelforschung ; 43(2): 163-6, 1993 Feb.
Article in English | MEDLINE | ID: mdl-8457240

ABSTRACT

In a search for new anthelmintic compounds, some pyrazinothiadiazine dioxide derivatives were synthesized. Their anthelmintic activity was tested against larva and preadult stages of Trichinella spiralis. The mode of action and acute toxicity of these compounds were investigated. Structure-activity relationships are discussed.


Subject(s)
Anthelmintics/pharmacology , Pyrazines/pharmacology , Animals , Anthelmintics/therapeutic use , Anthelmintics/toxicity , Chickens , Colchicine/pharmacokinetics , Colchicine/pharmacology , Colchicine/therapeutic use , Female , Folic Acid Antagonists , Lethal Dose 50 , Liver/drug effects , Liver/enzymology , Mice , Protein Binding/drug effects , Pyrazines/therapeutic use , Pyrazines/toxicity , Structure-Activity Relationship , Trichinella/drug effects , Trichinellosis/drug therapy , Trichinellosis/parasitology , Tubulin/drug effects , Tubulin/metabolism
9.
Int J Parasitol ; 22(3): 335-9, 1992 May.
Article in English | MEDLINE | ID: mdl-1639569

ABSTRACT

The viability of hydatid cysts developed in vitro for 90 days was assessed by implantation into mice. Cysts removed from mice at 270 days post-infection (p.i.) increased their size 13.5-fold and contained several brood capsules containing protoscoleces. Thus, cysts remain viable after prolonged in vitro culture. The implantation in mice of 15 cysts developed in vitro yielded an average of 10 cysts per mouse, which is indicative of a high survival rate in these experimental infections. The ultrastructural study of cysts recovered from mice 270 days p.i. showed that the germinal membrane was more compact than before implantation and several layers of tegumental cells had developed. Observations of cysts removed from mice indicated that the plasma membrane surrounding microtriches had prolongations opening into the laminated layer.


Subject(s)
Echinococcosis/parasitology , Echinococcus/growth & development , Animals , Echinococcus/ultrastructure , Mice , Microscopy, Electron
10.
Int J Parasitol ; 19(8): 945-7, 1989 Dec.
Article in English | MEDLINE | ID: mdl-2635167

ABSTRACT

The in vitro effects of levamisole and ivermectin against Echinococcus granulosus protoscoleces were studied by means of light and electron microscopy. Both drugs had a protoscolicidal activity that increased proportionally with increasing concentrations of the drugs. Ivermectin showed the more rapid effects and caused contraction and paralysis of protoscoleces. A paralyzing effect was also observed with levamisole, followed by irreversible tissue vacuolation leading to death.


Subject(s)
Echinococcus/drug effects , Ivermectin/pharmacology , Levamisole/pharmacology , Animals , Echinococcus/ultrastructure , Microscopy, Electron , Microscopy, Electron, Scanning
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