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1.
Diagnostics (Basel) ; 13(14)2023 Jul 20.
Article in English | MEDLINE | ID: mdl-37510176

ABSTRACT

(1) Background: Adolescent Idiopathic Scoliosis (AIS) is a three-dimensional (3D) spine deformity. The Cobb angle, evaluated with 2D radiography, is the gold standard to determine curve severity. The primary aim of this study was to evaluate the 3D spinal evaluation with rasterstereography in patients with AIS. The hypothesis was that rasterstereography reached higher accuracy than the gold standard 2D radiography. The second aim was to compare rasterstereography with 3D radiography. The hypothesis was that the rasterstereographic evaluation of patients with severe major scoliosis curves is closer to 3D radiography compared to the gold standard (2D radiography). (2) Methods: This is a prospective comparative study of a consecutive series of 53 patients, with the scoliosis curve evaluated with two 3D methods and the gold standard (2D radiography). (3) Results: The hypothesis that rasterstereography reached higher accuracy than the gold standard 2D radiography was validated for all curves. Even if all curves were highly correlated, both rasterstereography and 2D radiography scoliosis evaluation were underestimated for moderate/severe curves compared to 3D radiography. (4) Conclusions: The rasterstereographic evaluation of major curve scoliosis is not accurate enough to replace 2D radiography for moderate/severe curves. A longitudinal follow-up should be assessed in future studies to define the sensitivity of the detection of a significant change in the scoliotic mild and moderate curve (<40°).

2.
Spine (Phila Pa 1976) ; 46(19): 1326-1335, 2021 Oct 01.
Article in English | MEDLINE | ID: mdl-34517401

ABSTRACT

STUDY DESIGN: Retrospective review of prospective case-control study. OBJECTIVE: To compare minimally invasive scoliosis surgery (MIS) and posterior spinal fusion (PSF) in a large group of patients. SUMMARY OF BACKGROUND DATA: MIS, has been shown to have benefits over standard PSF in adolescent idiopathic scoliosis (AIS). METHODS: Radiographic, clinical, and operative review of a multi-institutional prospective database from 2013 to 2018. MIS patients with minimum 2-year XR follow up were compared with open PSF technique patients. RESULTS: Four hundred eighty five patients were included; 192 MIS and 293 PSF. Preoperative Cobb (P = 0.231) and kyphosis were similar (P = 0.501). Cobb correction was comparable (P = 0.46), however percent improvement in thoracic kyphosis was significantly higher in MIS (P < 0.001). MIS had significantly lower blood loss (P < 0.001), transfusions (P < 0.001), fixation points (P < 0.001), opioid consumption (P = 0.001), and hospital stay (P < 0.001). Operative time was shorter (P = 0.001) and 30-day complications rate was similar (P = 0.81). CONCLUSION: This is the largest study comparing the surgical outcomes of MIS and PSF. MIS patients benefit from increased kyphosis, fewer transfusion, lower opioid consumption, and shorter hospital stay with similar Cobb correction. Increased postoperative kyphosis is likely from muscle sparing dissection in MIS.Level of Evidence: 3.


Subject(s)
Scoliosis , Spinal Fusion , Adolescent , Case-Control Studies , Humans , Retrospective Studies , Scoliosis/diagnostic imaging , Scoliosis/surgery , Spinal Fusion/adverse effects , Thoracic Vertebrae , Treatment Outcome
3.
Bone Joint J ; 102-B(4): 506-512, 2020 Apr.
Article in English | MEDLINE | ID: mdl-32228081

ABSTRACT

AIMS: The direct posterior approach with subperiosteal dissection of the paraspinal muscles from the vertebrae is considered to be the standard approach for the surgical treatment of adolescent idiopathic scoliosis (AIS). We investigated whether or not a minimally-invasive surgery (MIS) technique could offer improved results. METHODS: Consecutive AIS patients treated with an MIS technique at two tertiary centres from June 2013 to March 2016 were retrospectively included. Preoperative patient deformity characteristics, perioperative parameters, power of deformity correction, and complications were studied. A total of 93 patients were included. The outcome of the first 25 patients and the latter 68 were compared as part of our safety analysis to examine the effect of the learning curve. RESULTS: In the first 25 cases, with a mean follow-up of 5.6 years (standard deviation (SD) 0.4), the mean preoperative major Cobb angle was 57.6° (SD 9.8°) and significantly corrected to mean 15.4° (SD 5.6°, 73% curve correction). The mean preoperative T5-T12 was 26.2 (SD 12.8) and significantly increased to mean 32.9 (SD 8.3). Both frontal and sagittal plane correction was conserved two years after surgery. The rate of perioperative complications was 12% and three further complications occurred (three deep delayed infection). In the latter cases, 68 patients were included with a mean follow-up time of three years (SD 0.6). The mean preoperative major Cobb angle was 58.4° (SD 9.2°) and significantly corrected to mean 20.4° (SD 7.3°).The mean preoperative T5-T12 kyphosis was 26.6° (SD 12.8°) and was significantly increased to mean 31.4° (SD 8.3°). Both frontal and sagittal correction was conserved two years after surgery. The perioperative (30 day) complication rate was 1.4%. Two (2.9%) additional complications occurred in two patients. CONCLUSION: MIS for AIS is associated with a significant correction of spine deformity in the frontal and sagittal planes, together with low estimated blood loss and short length of stay. The perioperative complication rate seems to be lower compared with the standard open technique based on the literature data. The longer-term safety of MIS for AIS needs to be documented with a larger cohort and compared with the standard posterior approach. Cite this article: Bone Joint J 2020;102-B(4):506-512.


Subject(s)
Minimally Invasive Surgical Procedures/methods , Scoliosis/surgery , Adolescent , Adult , Child , Female , Follow-Up Studies , Humans , Male , Minimally Invasive Surgical Procedures/adverse effects , Postoperative Complications , Radiography , Retrospective Studies , Scoliosis/diagnostic imaging , Scoliosis/pathology , Tomography, X-Ray Computed , Treatment Outcome , Young Adult
4.
Rev Med Suisse ; 13(550): 422-426, 2017 Feb 15.
Article in French | MEDLINE | ID: mdl-28714635

ABSTRACT

The rapid growth of the spine during the pubertal spurt requires greater vigilance for the pediatrician at the annual check during this period to detect the occurrence of scoliosis. Before confirming the diagnosis of idiopathic scoliosis, it is imperative to exclude a secondary cause with appropriate history and clinical examination, and in selective cases with additional testing. Any scoliosis detected during growth should be considered potentially progressive and sent to a specialist if it is equal to or exceeds 20° on the X-rays. Radiological changes of more than 5° during a 6 months interval must also motivate an appointment with a specialist. Regular clinical and radiological surveillance, every 6 months, remains imperative to confirm or deny this risk of progression and decide on treatment.


La forte croissance du rachis durant la période péripubertaire impose l'obligation d'une plus grande vigilance au cours des examens annuels chez le pédiatre, afin de dépister la survenue d'une scoliose. Avant d'en affirmer le caractère idiopathique, il est nécessaire d'écarter une cause secondaire par une anamnèse et un examen clinique ciblé, voire des examens complémentaires. Toute scoliose dépistée en période de croissance doit être considérée comme potentiellement évolutive et adressée auprès d'un spécialiste dès lors qu'elle atteint ou dépasse radiologiquement 20°. Une évolution radiologique de plus de 5° en 6 mois doit également motiver une consultation spécialisée. La surveillance radioclinique régulière, tous les 6 mois, reste donc un impératif pour confirmer ou infirmer ce risque évolutif et décider du traitement.


Subject(s)
Scoliosis/diagnosis , Scoliosis/therapy , Adolescent , Decision Trees , Humans
5.
Medicine (Baltimore) ; 96(9): e6203, 2017 Mar.
Article in English | MEDLINE | ID: mdl-28248876

ABSTRACT

RATIONALE: Obturator pyomyositis is a rare condition in children. Diagnosis is often delayed because of its rarity, and the vagaries of its presentation cause it to be easily be missed. Physicians should therefore familiarize themselves with this condition and consider it as a possible differential diagnosis in patients presenting with an acutely painful hip. Inflammatory syndrome is also frequent among sufferers and the MRI is a very sensitive diagnostic tool for obturator pyomyositis. Additionally, joint fluid aspirations and blood cultures are also useful in identifying the pathogen. The appropriate antibiotic therapy provides a rapid regression of symptoms during the early stage of pyomyositis. In cases of MRI-confirmed abscess, surgical treatment is indicated. PATIENT CONCERNS: Our report focuses on a case of obturator pyomyositis in a 9-year-old boy. The child was febrile for 5 days and could only manage to walk a few steps. His hip range of motion was restricted in all directions. In addition, the patient had presented pain and swelling of his right elbow for a day, with a restriction of motion in the joint. There was a clear inflammatory syndrome. A diagnosis of hip and elbow septic arthritis was suspected, and the child underwent joint aspiration of the both cited joints. The aspiration of the elbow returned pus. Conversely, no effusion was found in the hip aspiration. The administration of empiric intravenous antibiotherapy was started. DIAGNOSES: An MRI revealed an osteomyelitis of the ischio-pubic area associated with a subperiosteal abscess. INTERVENTIONS: Subsequently, 3 days after elbow arthrotomy, a surgical treatment was performed on the patient's right hip in order to evacuate the subperiosteal abscess and muscular collection because of the persistence of the patient's symptoms and inflammatory syndrome despite susceptible intravenous antibiotics. Postsurgery the patient showed steady improvement. LESSONS: Such cases demonstrate how diagnosis can be difficult because pelvic pyomyositis is often mistaken for more common pathologies such as septic arthritis, osteomyelitis, or appendicitis. This may delay the diagnosis or refer misdiagnosis. We discuss this rare infection in light of the literature with particular reference to its incidence, clinical features, bacteriological etiology, biological, and radiological presentation, and above all, its treatment.


Subject(s)
Osteomyelitis/diagnosis , Pyomyositis/diagnosis , Child , Humans , Male , Osteomyelitis/therapy , Pyomyositis/therapy
6.
J Inorg Biochem ; 152: 174-9, 2015 Nov.
Article in English | MEDLINE | ID: mdl-26404568

ABSTRACT

Exostosis (or osteochondroma) is the most common benign bone tumor encountered in children and adults. Exostoses may occur as solitary or multiple tumors (in the autosomal syndromes of hereditary multiple exostoses). Exostoses are composed of cortical and medullary bone covered by an overlying hyaline cartilage cap. We have searched iron (Fe) and aluminum (Al) in the matrix of cortical and trabecular bone of 30 patients with exostosis. Al(3+) and Fe(3+) are two cations which can substitute calcium in the hydroxyapatite crystals of the bone matrix. The bone samples were removed surgically and were studied undecalcified. Perls' Prussian blue staining (for Fe) and solochrome azurine B (for Al) were used on the histological sections of the tumors. Al(3+) was detected histochemically in 21/30 patients as linear bands deposited by the osteoblasts. Fe(3+) was detected in 10 out of these 21 patients as linear bands in the same locations. Fe(3+) and Al(3+) were not identified in the bone matrix of a control group of 20 osteoporotic patients. Energy X-ray Dispersive Spectrometry failed to identify Fe and Al in bone of these tumors due to the low sensitivity of the method. Wavelength Dispersive Spectrometry identified them but the concentrations were very low. Histochemistry appears a very sensitive method for Fe(3+) and Al(3+) in bone.The presence of these two metals in the exostoses advocates for a disturbed metabolism of osteoblasts which can deposit these metals into the bone matrix, similar to which is observed in case of hemochromatosis with Fe(3+).


Subject(s)
Aluminum/analysis , Bone Matrix/chemistry , Exostoses/metabolism , Iron/analysis , Adolescent , Adult , Aged , Aluminum/metabolism , Bone Matrix/metabolism , Case-Control Studies , Child , Child, Preschool , Female , Humans , Iron/metabolism , Male , Middle Aged
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