1.
Bioorg Med Chem
; 18(18): 6742-7, 2010 Sep 15.
Article
in English
| MEDLINE
| ID: mdl-20729093
ABSTRACT
In this work the antiproliferative activity of goniothalamin (1), both in racemic and in its enantiomeric pure forms, in a solid tumor experimental model using laboratory animals is described. The antiedematogenic activity displayed by racemic 1 in the carrageenan edema model in mice together with the reduction of Ehrlich solid tumor model suggest a relationship between anticancer and antiinflammatory activities with the antiinflammatory activity favoring the antiproliferative activity itself.