Inflammation and quality of life in later life: findings from the health, well-being and aging study (SABE).

BACKGROUND: Few studies have specifically investigated the inverse relationship between reduced quality of life in different domains and elevated C-reactive protein (CRP) serum levels in older adults. Therefore, this study investigates the cross-sectional association between quality of life and inflammation in older Brazilian adults. METHODS: Data were collected from 1255 participants from the third wave (2010) of the Brazilian Health, Well-being and Aging study (SABE), a community-based cohort study of aging. Inflammation was assessed using CRP serum levels and quality of life (QoL) was measured using the 12-item Short-Form Health Survey (SF-12) questionnaire. The covariates included age, sex, education level, financial sufficiency, number of non-communicable diseases, self-reported doctor diagnosed diseases, Activity of Daily Living (ADL) difficulties, Body Mass Index (BMI), and waist circumference. RESULTS: The fully adjusted models showed that older adults with low scores in the physical domain of the SF12 (OR 1.34, 95%CI 1.02;1.77) and high BMI values (> 30) (OR 2.05, 95%CI 1.50;2.81) were more likely to present high CRP serum levels. CONCLUSION: Our findings suggest a significant association of lower scores in the physical domain of quality of life and the presence of obesity with high CRP serum levels.

Healthcare Expenditures Related to BMI and Physical Activity Among Diabetic Older People: Cross-sectional Analysis of Sabe Study.

BACKGROUND: The age is a variable positively related to healthcare expenditures on diabetes (DM), however other factors could also be associated. Physical activity, normal weight and walking habit could be inversely associated to healthcare expenditures related to DM control. The aim of this study was to describe healthcare diabetic-related expenditures and analyze the associations with Body Mass Index (BMI), Physical Activity Level (PAL), and walking habit among the elderly Brazilians. METHODS: A cross-sectional analysis was carried out on a population-based study (SABE Study) in Brazil. Healthcare expenditures were estimated for the medicine prescriptions, outpatient service and hospitalization. The sample was classified according to BMI, the PAL, and according to weekly frequency of walking habit.The annual healthcare expenditures were estimated, and the multiple logistic regression was used to analyze the associations between variables. RESULTS: The sample included 295 elderly diabetics, with a mean age 70 years. The excess weight group presented significantly higher annual expenditures with medicine prescriptions, hospitalization, and outpatient services. Absence of walking habit was related to higher costs and inversely associated to higher expenditures to medicine prescriptions (OR 2.82, IC95% 1.48 - 5.40) and hospitalizations (OR 5.79, IC95% 1.10 - 10.93), independent of BMI, sex, age and the presence of hypertension. CONCLUSION: BMI and insufficient PAL were associated to higher public expenditures related to DM control in elderly people. Walking habit was inversely associated to healthcare expenditures on behalf of the diabetes control among Brazilian elderly population.

Expenditures of medicine use in hypertensive/diabetic elderly and physical activity and engagement in walking: cross secctional analysis of SABE Survey.

BACKGROUND: The literature shows the inverse association between physical activity level (PAL) and chronic diseases that have a significant burden over health care costs. However, in upper-middle income countries and in elderly population this information are scarce. OBJECTIVE: To describe the annual drug expenditures for the hypertensive and diabetic elderly population in Brazil and to analyze the association with PAL and engagement in walking. METHODS: This cross sectional study is part of SABE Survey and comprised 806 hypertensive and/or diabetic elderly (≥60 years old). The annual expenditures of medicine use was estimated for all medications for hypertension and/or diabetes they were taking. The PAL was considered insufficient when moderate physical activity was <150 min/week or vigorous physical activity was < 75 min/week. Engagement in walking was considered by at least 1 day a week. All expenditures were presented through the descriptive values (in American Dollars US$) according PAL and engagement in walking. The association analysis between annual expenditures, PAL and engagement in walking were performed by multiple logistic regression models adjusted for gender, age and body mass index. RESULTS: The average annual cost was higher in diabetic and insufficient physically activity elderly. The 1-year estimated.cost was US$ 73386,09 and 295% higher in insufficiently physically active. Older people who reported not walking had a higher risk to higher annual expenditures of medicine use (OR = 1.57, 95% CI 1.03-2.40). CONCLUSIONS: The annual expenditures of medicine use for controlling hypertension and diabetes of Brazilian elderly were higher and inversely associated with physical activity level and engagement in walking.

Strength training increases walking tolerance in intermittent claudication patients: randomized trial.

OBJECTIVE: To analyze the effects of strength training (ST) in walking capacity in patients with intermittent claudication (IC) compared with walking training (WT) effects. METHODS: Thirty patients with IC were randomized into ST and WT. Both groups trained twice a week for 12 weeks at the same rate of perceived exertion. ST consisted of three sets of 10 repetitions of whole body exercises. WT consisted of 15 bouts of 2-minute walking. Before and after the training program walking capacity, peak VO(2), VO(2) at the first stage of treadmill test, ankle brachial index, ischemic window, and knee extension strength were measured. RESULTS: ST improved initial claudication distance (358 +/- 224 vs 504 +/- 276 meters; P < .01), total walking distance (618 +/- 282 to 775 +/- 334 meters; P < .01), VO(2) at the first stage of treadmill test (9.7 +/- 2.6 vs 8.1 +/- 1.7 mL.kg(-1).minute; P < .01), ischemic window (0.81 +/- 1.16 vs 0.43 +/- 0.47 mm Hg minute meters(-1); P = .04), and knee extension strength (19 +/- 9 vs 21 +/- 8 kg and 21 +/- 9 vs 23 +/- 9; P < .01). Strength increases correlated with the increase in initial claudication distance (r = 0.64; P = .01) and with the decrease in VO(2) measured at the first stage of the treadmill test (r = -0.52; P = .04 and r = -0.55; P = .03). Adaptations following ST were similar to the ones observed after WT; however, patients reported lower pain during ST than WT (P < .01). CONCLUSION: ST improves functional limitation similarly to WT but it produces lower pain, suggesting that this type of exercise could be useful and should be considered in patients with IC.

Pain threshold is achieved at intensity above anaerobic threshold in patients with intermittent claudication.

PURPOSE: Walking training is considered as the first treatment option for patients with peripheral arterial disease and intermittent claudication (IC). Walking exercise has been prescribed for these patients by relative intensity of peak oxygen uptake (VO2peak), ranging from 40% to 70% VO2peak, or pain threshold (PT). However, the relationship between these methods and anaerobic threshold (AT), which is considered one of the best metabolic markers for establishing training intensity, has not been analyzed. Thus, the aim of this study was to compare, in IC patients, the physiological responses at exercise intensities usually prescribed for training (% VO2peak or % PT) with the ones observed at AT. METHODS: Thirty-three IC patients performed maximal graded cardiopulmonary treadmill test to assess exercise tolerance. During the test, heart rate (HR), VO2, and systolic blood pressure were measured and responses were analyzed at the following: 40% of VO2peak; 70% of VO2peak; AT; and PT. RESULTS: Heart rate and VO2 at 40% and 70% of VO2peak were lower than those at AT (HR: -13 +/- 9% and -3 +/- 8%, P < .01, respectively; VO2: -52 +/- 12% and -13 +/- 15%, P < .01, respectively). Conversely, HR and VO2 at PT were slightly higher than those at AT (HR: +3 +/- 8%, P < .01; VO2: +6 +/- 15%, P = .04). None of the patients achieved the respiratory compensation point. CONCLUSION: Prescribing exercise for IC patients between 40% and 70% of VO2peak will induce a lower stimulus than that at AT, whereas prescribing exercise at PT will result in a stimulus above AT. Thus, prescribing exercise training for IC patients on the basis of PT will probably produce a greater metabolic stimulus, promoting better cardiovascular benefits.

[Nutritional status and physical performance of elderly in the city of São Paulo]. / Estado nutricional e desempenho motor de idosos de São Paulo.

OBJECTIVE: To evaluate the nutritional status (NS) and its association with physical performance tests (PPT) of elderly in the city of São Paulo, Brazil. METHODS: Design--Cross-sectional epidemiological study, in a population on a household basis as part of a multicenter study (the SABE Survey), coordinated by the Pan-American Health Organization. Setting-- From January/2000 to March/2001, the SABE survey comprised 2143 elderly (>or=60 yrs old), of both genders, selected by probabilistic sampling. Of these, 1894 (88.4%) took part in this study. The elderly were separated by gender and age group (60-69, 70-79 and>or=80 yrs old) for the tests and the NS was evaluated according to the Body Mass Index (BMI): underweight (BMIor=28 kg/m2). The PPTs included timed, repeated "chair stand" (CS), timed "pick up a pen" (PP) and standing balance (SB). The associations (CS and PP) were verified by the Cox Regression analysis and (SB) by the chi square test. RESULTS: There were statistically significant associations between PP and SB and obese women. CONCLUSION: Results showed association between nutritional status and functional capacity for women and obesity was the nutritional condition associated with the worst performance in the tests. Gender and age group should be considered in the association between nutritional status and physical performance.

[Anthropometry of elderly people living in geriatric institutions, Brazil]. / Antropometria de idosos residentes em instituições geriátricas, Fortaleza, CE.

OBJECTIVE: To provide anthropometric and body composition information on elderly people living in geriatric institutions. METHODS: Three-hundred and five elderly people, of both sexes, living in six geriatric institutions in Fortaleza were assessed. The following anthropometric variables were studied: weight, height, body mass index, mid-arm circumference, triceps skinfold thickness, arm muscle circumference, and corrected arm-muscle area. The body mass index was calculated as weight divided by the square of the height (m2). The arm muscle circumference and corrected arm-muscle area were calculated using specific equations. The results are presented as means, standard deviations and percentiles (5th, 10th, 25th, 50th, 75th, 90th and 95th). The analyses included Student t-test to detect differences in mean values of the variables between both sexes. Age impact was investigated by ANOVA. RESULTS: In all variables, mean values in men were higher than those in women, except for triceps skinfold thickness . The mean difference of the variables body mass index and mid-arm circumference for both sexes were not statistically significant (p>0.05). Age has significantly contributed to reducing the variables' values. This means that specific reference standards are needed for elderly people. CONCLUSIONS: Despite being institutionalized, there was seen a trend of decreasing anthropometric values in the study population similar to that found in other studies of elderly people but with different values. Thereby, such values could be useful in the nutritional assessment of institutionalized elderly people.