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J Neurol Sci ; 249(1): 19-24, 2006 Nov 01.
Article in English | MEDLINE | ID: mdl-16870213

ABSTRACT

Neurological manifestation is considered a rare complication of dengue infection. Neurological and cerebrospinal fluid (CSF) findings of 13 patients with dengue infection were studied. Seven patients had encephalitis, two had myelitis and four showed Guillain-Barré syndrome (GBS). No alteration in CSF was found from 57% of those with encephalitis. Patients with GBS and myelitis showed a CSF-blood barrier dysfunction. The differences in the CSF may be related to the location of the lesion and multiple mechanisms of the disease in the nervous system.


Subject(s)
Cerebrospinal Fluid Proteins/immunology , Dengue Virus/immunology , Dengue/complications , Encephalitis, Viral/diagnosis , Guillain-Barre Syndrome/diagnosis , Myelitis/diagnosis , Adult , Aged , Cerebrospinal Fluid Proteins/analysis , Child , Encephalitis, Viral/cerebrospinal fluid , Encephalitis, Viral/virology , Female , Guillain-Barre Syndrome/cerebrospinal fluid , Guillain-Barre Syndrome/virology , Humans , Immunoglobulin M/cerebrospinal fluid , Magnetic Resonance Imaging , Male , Middle Aged , Myelitis/cerebrospinal fluid , Myelitis/virology , Predictive Value of Tests , Serotyping , Spinal Cord/pathology , Spinal Cord/physiopathology , Spinal Cord/virology
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