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1.
Tijdschr Psychiatr ; 55(4): 247-57, 2013.
Article in Dutch | MEDLINE | ID: mdl-23595839

ABSTRACT

BACKGROUND: In psychodynamic psychotherapy it is assumed that insight-fostering interventions lead to better results when used with patients who have relatively strong personality structures. AIM: To investigate to what extent the use of supportive or insight-fostering interventions is determined by sociodemographic variables, the severity, duration and recurrence of depression and defence style and to find out whether the type of intervention used can predict the treatment outcome of psychotherapy in depression. METHOD: The study-group consisted of 147 depressed patients with or without a comorbid personality disorder who had been treated with supportive PsychoDynamic Therapy (PDT) with or without medication and for whom the Therapist Evaluation Form (TEF) was available. On the TEF the therapist assessed the patients' defence style and the therapeutic technique that was used. The most important outcome measure was the Hamilton Depression Rating Scale (HAM-D). RESULTS: No correlation was found between technique used and sociodemographic characteristics or the severity and duration of the depression. Insight-fostering interventions were related to better treatment outcomes. Not only age and educational level but also defence style turned out to be confounding variables in the relationship between technique and outcome. We found no interaction between treatment success and insight-fostering interventions in patients who used mature defence styles. CONCLUSION: In our study it was defence style as evaluated by the therapist rather than the technique used which was the strongest independent predictor of a successful outcome. This indicates that patients with primitive defence styles may also benefit from insight-fostering interventions.


Subject(s)
Depression/psychology , Depression/therapy , Outcome and Process Assessment, Health Care , Psychotherapy/methods , Age Factors , Aged , Antidepressive Agents/therapeutic use , Combined Modality Therapy , Defense Mechanisms , Educational Status , Female , Humans , Male , Middle Aged , Predictive Value of Tests , Prognosis , Psychotherapeutic Processes , Treatment Outcome
2.
Acta Psychiatr Scand ; 53(4): 271-6, 1976 Apr.
Article in English | MEDLINE | ID: mdl-775889

ABSTRACT

In a double-blind study of 44 depressive in-patients, treatment with placebo appeared to give equally good results as did treatment with thioridazine. Both treatment procedures permitted the additional prescription of chlordiazepoxide when the patient's condition indicated the need for anxiety reduction. The use of chlordiazepoxide was more frequently necessary with treatment with placebo than with treatment with thioridazine.


Subject(s)
Depression/drug therapy , Thioridazine/therapeutic use , Adult , Anxiety/drug therapy , Chlordiazepoxide/therapeutic use , Clinical Trials as Topic , Drug Evaluation , Female , Humans , Male , Middle Aged , Placebos
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