ABSTRACT
This note describes the design and testing of a programmable pulsatile flow pump using an Arduino micro-controller. The goal of this work is to build a compact and affordable system that can relatively easily be programmed to generate physiological waveforms. The system described here was designed to be used in an in-vitro set-up for vascular access hemodynamics research, and hence incorporates a gear pump that delivers a mean flow of 900 ml/min in a test flow loop, and a peak flow of 1106 ml/min. After a number of simple identification experiments to assess the dynamic behaviour of the system, a feed-forward control routine was implemented. The resulting system was shown to be able to produce the targeted representative waveform with less than 3.6% error. Finally, we outline how to further increase the accuracy of the system, and how to adapt it to specific user needs.
Subject(s)
Heart Function Tests/instrumentation , Pulsatile Flow , Equipment Design , Nonlinear DynamicsABSTRACT
The support vector machine (SVM) is a method for classification and for function approximation. This method commonly makes use of an /spl epsi/-insensitive cost function, meaning that errors smaller than /spl epsi/ remain unpunished. As an alternative, a least squares support vector machine (LSSVM) uses a quadratic cost function. When the LSSVM method is used for function approximation, a nonsparse solution is obtained. The sparseness is imposed by pruning, i.e., recursively solving the approximation problem and subsequently omitting data that has a small error in the previous pass. However, omitting data with a small approximation error in the previous pass does not reliably predict what the error will be after the sample has been omitted. In this paper, a procedure is introduced that selects from a data set the training sample that will introduce the smallest approximation error when it will be omitted. It is shown that this pruning scheme outperforms the standard one.