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Biosci Rep ; 22(5-6): 549-54, 2002.
Article in English | MEDLINE | ID: mdl-12635852

ABSTRACT

We present a method for labeling bone marrow haematopoietic progenitor cells with iron particles. Labeling was assessed by magnetic resonance imaging and electron microscopy. Labeling with iron particles could allow the following by imaging techniques of haematopoietic cells in physiologic and pathologic conditions such as the engraftment of haematopoietic progenitor cells or the migration of myelomonocytic cells in inflammatory diseases.


Subject(s)
Hematopoietic Stem Cells/ultrastructure , Image Cytometry/methods , Iron , Magnetic Resonance Imaging/methods , Microscopy, Electron/methods , Oxides , Animals , Cell Movement/physiology , Dextrans , Ferrosoferric Oxide , Hematopoietic Stem Cell Transplantation/methods , Hematopoietic Stem Cells/metabolism , Image Cytometry/instrumentation , Inflammation/physiopathology , Magnetic Resonance Imaging/instrumentation , Magnetite Nanoparticles , Male , Microscopy, Electron/instrumentation , Rats , Rats, Sprague-Dawley
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