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Article in English | MEDLINE | ID: mdl-6121674

ABSTRACT

1. The effect of Dieldrin on phospholipid content and composition was compared in adult frog liver and in early embryos. 2. Male frogs are more resistant to acute Dieldrin treatment than females. Total phospholipids content increases in the liver of male animals while in females decreases. 3. Early embryo development was not affected morphologically by the addition of 0.02-10.0 mg of Dieldrin/1; however phospholipid content and composition was altered. 4. Adaptive changes in the embryo due to chronically administered Dieldrin is suggested.


Subject(s)
Bufonidae/metabolism , Dieldrin/pharmacology , Liver/metabolism , Phospholipids/metabolism , Animals , Bufonidae/embryology , Cholesterol/metabolism , Female , Gastrula/metabolism , Liver/embryology , Male , Microsomes, Liver/metabolism
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