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1.
Mol Immunol ; 156: 148-155, 2023 04.
Article in English | MEDLINE | ID: mdl-36921489

ABSTRACT

Vaccines induce specific long-term immunological memory against pathogens, preventing the worsening of diseases. The COVID-19 health emergency has caused more than 6 million deaths and started a race for vaccine development. Antibody response to COVID-19 vaccines has been investigated primarily in healthcare workers. The heterogeneity of immune responses and the behavior of this response in particular groups were still very little explored. In this review, we discuss whether antibody responses after vaccination are influenced by age, gender, previous SARS-CoV-2 infection, or pre-existing diseases.


Subject(s)
COVID-19 , Humans , COVID-19/prevention & control , Antibody Formation , COVID-19 Vaccines , Preexisting Condition Coverage , SARS-CoV-2 , Vaccination , Antibodies, Viral
2.
Emerg Infect Dis ; 28(6): 1237-1240, 2022 06.
Article in English | MEDLINE | ID: mdl-35421324

ABSTRACT

We evaluated the longitudinal dynamics of antibody response to the SARS-CoV-2 vaccine CoronaVac and the effect of a booster dose of BNT162b2 vaccine. We found a robust antibody response after the second dose of CoronaVac that wanes over time. The response was recovered by BNT162b2, which boosted anti-spike antibody titers.


Subject(s)
COVID-19 , Vaccines , Antibodies, Viral , Antibody Formation , BNT162 Vaccine , COVID-19/prevention & control , COVID-19 Vaccines , Humans , SARS-CoV-2
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