ABSTRACT
Semen samples were obtained from 28 infertile men referred for AIH. The percentage morphologically normal sperm was assessed on Papanicolaou stained smears before and after semen processing. The percentage of normal sperm increased significantly (p less than 0.005). It would seem that the semen processing procedure increased the number of morphologically normal sperm, which could theoretically improve the results of AIH.
Subject(s)
Infertility, Male , Semen/cytology , Spermatozoa/cytology , Humans , Male , Sperm Count , Sperm MotilityABSTRACT
the ultimate goal of any clinical programme treating infertility by means of in vitro fertilisation and embryo replacement is to maximise the number of patients who become pregnant in a treatment cycle. A 12% pregnancy rate was previously reported from this unit. Following the instigation of changes and further modifications, an overall success rate of 27% per patient was obtained in phase II. The reasons for this improved success are hard to pinpoint, but experience and changes in methodology probably play a role. These changes are described and the results discussed.
Subject(s)
Fertilization in Vitro/methods , Adult , Age Factors , Embryo Transfer/methods , Female , Humans , Ovulation Induction/methods , South AfricaABSTRACT
Details of the in vitro fertilization and embryo transfer programme at the Department of Obstetrics and Gynaecology of the H. F. Verwoerd Hospital and the University of Pretoria are presented. From 1 March 1982 to 30 November 1983, 67 cycles in 47 patients were induced using clomiphene citrate and human chorionic gonadotrophin (hCG) (46 patients) and human postmenopausal gonadotrophin/hCG (1 patient). In 5 patients ovum recovery was unsuccessful owing to severe adhesions. In the remaining 42 patients 59 oocyte recoveries out of a total of 62 attempts were successful, a 95% recovery rate. One hundred and seventy-nine ova were recovered (2,9 per laparoscopy), of which 143 (80%) were viable. Forty-six per cent of fertilized ova cleaved actively. Forty-one transfers of 66 embryos (average 1,6 embryos per transfer) resulted in 5 pregnancies (12% pregnancy rate per transfer). Three preclinical pregnancies aborted spontaneously. Two pregnancies are ongoing at 30 and 32 weeks' gestation. Thus, the programme has so far led to 2 third-trimester pregnancies. Consolidation and refinement of techniques should lead to a steady increase in success at this centre.
