ABSTRACT
OBJECTIVE: To assess changes in the great saphenous vein (GSV) after foam sclerotherapy for varicose veins. MATERIALS AND METHODS: This was a prospective study of 33 patients who were treated with polidocanol foam sclerotherapy after having had varicose veins with a clinical severity-etiology-anatomy-pathophysiology classification of C4-C6 for three months. The patients were evaluated by ultrasound before, during, and after the procedure (on post-procedure days 7, 15, 30, 60, and 90). The GSV diameter, the rate of venous occlusion, and the rate of reflux elimination were determined. Two patients were excluded for having a history of deep vein thrombosis history, and one was excluded for having bronchial asthma. RESULTS: Thirty patients (26 females and 4 males, with mean age of 62 years) completed the protocol. The mean pre-procedure GSV diameter was 6.0 ± 0.32 mm (range, 3.6-11.2 mm). During the sclerotherapy, the mean GSV diameter was reduced to 1.9 ± 0.15 mm (range, 0.6-3.8 mm). On post-procedure day 7, the mean GSV diameter increased to 6.3 ± 0.28 mm (range, 3.9-9.7 mm). On post-procedure day 90, the mean GSV diameter was 4.0 ± 0.22 mm (range, 1.9-8.2 mm). The rate of GSV reflux was significantly lower in the assessment performed on post-procedure day 90 than in the pre-procedure assessment (p < 0.0028). CONCLUSION: On the basis of our ultrasound analysis, we can conclude that foam sclerotherapy for varicose veins results in a significant reduction in GSV diameter, as well as in the elimination of GSV reflux.
ABSTRACT
The duplex exam is widely used in the diagnosis of peripheral arterial occlusive disease. It presents some drawbacks, however, such as calcified plaques, sequential stenosis, and time-consuming examinations. A type of waveform analysis, referred to in this study as segmental analysis, was conducted to try to find solutions to these problems. Parameters of waveform analysis (peak systolic velocity, acceleration time, pulsatility, and resistance indices) taken at the common femoral and popliteal arteries in 177 arterial segments (aortoiliac and femoropopliteal) were compared to angiography results in a prospective manner. The statistical analysis showed an accuracy rate above 95% for all parameters in defining hemodynamic-significant (stenosis and occlusions) lesions in both segments. Also, a combination of measurements (parallel tests) was used to differentiate between hemodynamic-significant stenosis and occlusions, showing sensitivity and specificity rates between 84.8% and 94.8%. Findings from this study show that the hemodynamics of an arterial segment can be evaluated by segmental waveform analysis. It can also be used as a screening test for peripheral arterial occlusive diseases alone or combined with the standard duplex color exam.
