ABSTRACT
There are few papers about physiological indices in Callithrix penicillata, an increasing primate model in biomedicine. We investigated levels of plasmatic cortisol, plasmatic glucose, free fatty acids, blood cells, tympanic temperature, rectal temperature in C. penicllata, under a fast restraint. Measures of body and weight were accomplished. Males and females were not different regarding any measurements. Body measurements indicated differences between adults and juveniles. Adults showed higher hematocrit and a tendency for higher free fatty acids than juveniles. Right tympanic temperature was higher in adults than juveniles. This result suggests a higher reaction metabolism in adults than juveniles under a restraint stress. Due to the short-time of collecting the data, plasmatic cortisol did not influence physiological parameters. Therefore, we suggest that present results could be considered referential values of C. penicillata physiology.
Subject(s)
Animals, Zoo , Callithrix/physiology , Age Factors , Animals , Blood Cell Count , Blood Glucose , Body Temperature , Body Weight , Brazil , Fatty Acids, Nonesterified/metabolism , Female , Hematocrit , Hydrocortisone/blood , Male , Reference Values , Sex FactorsABSTRACT
OBJECTIVES: Lymphoma is the most frequent testicular malignancy in men over 60 years of age. Even though patients present initially with localized disease, the high incidence of bilateral involvement, synchronous or not, and early systemic dissemination are characteristic of these neoplasms. Sometimes the interval between tumor involvement of both testes is long. The question is raised whether either the patient has a predisposition to present new clones of transformed lymphocytes, or the same disease using the same pathway from a systemic reservoir infiltrates the contralateral testis. METHOD: Polymerase chain reaction and DNA sequencing were used to detect immunoglobulin heavy chain (IgH) rearrangement in paraffin-embedded specimens from asynchronous tumors affecting the right and left testis of a 85-year-old man with an interval period of 13 months. RESULTS: Both tumors showed the same IgH rearrangement. CONCLUSIONS: The lymphoma affecting the left and right testis derived from the same clone. It makes a strong case that lymphoma of the testis is the first manifestation of a systemic disease and should be treated aggressively early at the beginning of the disease.
