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Life Sci ; 38(10): 923-7, 1986 Mar 10.
Article in English | MEDLINE | ID: mdl-2869393

ABSTRACT

A comparative study was conducted on the ability of bonellin, the green pigment of Bonellia viridis, and hematoporphyrin to induce photoperoxidation of lipids in solutions and in erythrocyte ghosts. The inhibiting effect of two free radical scavangers, acetyl-homocysteine-thiolactone and meclofenoxate, indicates that bonellin-induced lipid peroxidation involves free radical production. The relation between bonellin and defence mechanism of Bonellia viridis is discussed.


Subject(s)
Erythrocyte Membrane/metabolism , Lipid Peroxides/blood , Porphyrins/pharmacology , Cholesterol , Erythrocyte Membrane/drug effects , Free Radicals , Hematoporphyrins/pharmacology , Humans , Linolenic Acids , Meclofenoxate/pharmacology , Photochemistry , Solutions , Thiophenes/pharmacology , alpha-Linolenic Acid
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