ABSTRACT
PURPOSE: The purpose of this study was to evaluate the histological features of the pulp tissue in primary pig teeth submitted to pulpotomy and capped with calcium hydroxide-based and standardized propolis extract-based pastes, and the combination of these pastes. METHODS: Nine 4-month-old male pigs were used in this study, which were distributed into 4 groups, according to the studied pastes: Group 1-calcium hydroxide; Group2-standardized propolis extract; Group 3-combination of pastes 1 and 2 in the proportion 1:1; and Group 4-control. The teeth used for the pulpotomy were the 4 mandibular primary incisors. RESULTS: After 7, 21, and 42 days, the animals were killed and the teeth were re-moved for histological analysis. At 42 days, all teeth in Groups 1 to 3 presented a complete hardtissue barrier and the pulp tissue beneath was without inflammation. CONCLUSION: According to these findings, calcium hydroxide and standardized propolis extract favored the formation of a hard tissue barrier in primary pig teeth submitted to pulpotomy.
Subject(s)
Calcium Hydroxide/pharmacology , Dental Pulp Capping/methods , Incisor/surgery , Propolis/pharmacology , Pulpotomy , Animals , Dental Pulp Necrosis , Male , Swine , Tooth, Deciduous/surgeryABSTRACT
OBJECTIVE: The aim of this study was to evaluate the biocompatibility of the root canal sealer Epiphany in rat subcutaneous tissues. STUDY DESIGN: Polyethylene tubes were filled with the sealer (I: Epiphany; II: photoactivated Epiphany; III: Epiphany associated with self-etch primer; IV: photoactivated Epiphany associated with primer; and V: control group) and later implanted into 4 different regions of the dorsum of 15 adult male rats (Rattus novergicus, Albinus Wistar). After 7, 21, and 42 days, 5 animals were killed, obtaining 4 samples per group, in addition to the control group, at each analyzed time. RESULTS: In all periods, Epiphany induced a mild inflammatory reaction. However, in group II, in which the primer was not used, extensive necrosis and a moderate to intense inflammatory reaction were observed, mainly after 7 and 21 days. CONCLUSION: Epiphany sealer appears biocompatible when tested on rat subcutaneous tissues.