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Rev Esp Fisiol ; 42(4): 529-33, 1986 Dec.
Article in Spanish | MEDLINE | ID: mdl-3563079

ABSTRACT

Previous references showed that the histamine injected peripherically produced a deterioration of the learning in experimental animals. The effects of 100 and 200 micrograms of histamine administered in the cerebral lateral ventricle, have been tested using an experimental paradigm which isolated attentional, motivational, and motor factor from the complex learned behavior. The obtained results showed to be similar to those produced by peripheric injection, and demonstrated a worsening in attentional, motivational, and motor parameters.


Subject(s)
Behavior, Animal/drug effects , Histamine/pharmacology , Animals , Eliminative Behavior, Animal/drug effects , Injections, Intraventricular , Learning/drug effects , Male , Rats , Rats, Inbred Strains
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