[Acute glomerulonephritis in children: long-term prognosis]. / Glomerulonefritis aguda en el niño: pronóstico a largo plazo.

Sixty-five children were studied for over five years following an acute glomerulonephritis episode. Proteinuria was detected in 15 but in one, it was massive proteinuria with edema and low renal function. The other 14 children were asymptomatic and proteinuria was close to or below 0.5 gms/24hs. Only one out of 10 renal biopsies was normal. Focal mesangial proliferation was described in 9. Such renal lesion was considered as residual rather than active. From these results it is concluded that the prognosis of acute glomerulonephritis in children is good in 98% of cases.

[Familial incidence of post-streptococcal glomerulonephritis]. / Incidencia familiar de la glomerulonefritis postestrepotocócica.

The investigation on siblings of AGN patients has shown a streptococcus carrier evidence of 45%, while glomerulonephritis incidence was 15%. These data allowed us to classify our population as highly susceptible to bacterial dissemination and to the development of non-suppurative complications. Renal compromise was clinical and histologically classified. Subclinical forms showed glomerular lesions of mesangial localization, while clinical forms exhibited variable degrees of cellular proliferation. All patients recovered except one who died of a rapidly progressive form.

[Acute glomerulonephritis in children. I. Clinical manifestations]. / Glomerulonefritis aguda en el niño I. Manifestaciones clínicas.

The symptoms and short-term evolution of 617 patients with acute glomerulonephritis are discussed. Edema was the most frequent symptom (93%) at the time that gross hematuria was only present in 65% of cases. On the other side, heart failure was detected in 33% of patients and neurological symptoms in 6%. Short-term follow-up of 381 of these patients show that microscopic hematuria cleared up after six months in 73% of cases, but lasted more than one year in only 4% of patients.