[Summary of the consensus document: "Clinical practice guide for the management of low cardiac output syndrome in the postoperative period of heart surgery"]. / Resumen del documento de consenso «Guías de práctica clínica para el manejo del síndrome de bajo gasto cardiaco en el postoperatorio de cirugía cardiaca¼

Low cardiac output syndrome is a potential complication in cardiac surgery patients and is associated with increased morbidity and mortality. This guide provides recommendations for the management of these patients, immediately after surgery and following admission to the ICU. The recommendations are grouped into different sections, addressing from the most basic concepts such as definition of the disorder to the different sections of basic and advanced monitoring, and culminating with the complex management of this syndrome. We propose an algorithm for initial management, as well as two others for ventricular failure (predominantly left or right). Most of the recommendations are based on expert consensus, due to the lack of randomized trials of adequate design and sample size in patients of this kind. The quality of evidence and strength of the recommendations were based on the GRADE methodology. The guide is presented as a list of recommendations (with the level of evidence for each recommendation) for each question on the selected topic. For each question, justification of the recommendations is then provided.

[Clinical practice guide for the management of low cardiac output syndrome in the postoperative period of heart surgery]. / Guías de práctica clínica para el manejo del síndrome de bajo gasto cardíaco en el postoperatorio de cirugía cardíaca.

The low cardiac output syndrome is a potential complication in cardiac surgery patients and associated with increased morbidity and mortality. This guide is to provide recommendations for the management of these patients, immediately after surgery, admitted to the ICU. The recommendations are grouped into different sections, trying to answer from the most basic concepts such as the definition to the different sections of basic and advanced monitoring and ending with the complex management of this syndrome. We propose an algorithm for initial management, as well as two other for ventricular failure (predominantly left or right). Most of the recommendations are based on expert consensus because of the lack of randomized trials of adequate design and sample size in this group of patients. The quality of evidence and strength of the recommendations were made following the GRADE methodology. The guide is presented as a list of recommendations (and level of evidence for each recommendation) for each question on the selected topic. Then for each question, we proceed to the justification of the recommendations.

Nasolacrimal polyurethane stent placement for epiphora: technical long-term results.

PURPOSE: To assess technical problems related to implantation of a polyurethane stent to treat obstructive epiphora, and to assess the long-term patency of the nasolacrimal system. MATERIALS AND METHODS: Fluoroscopically guided placement of a polyurethane nasolacrimal stent was performed in 70 obstructed lacrimal systems of 62 patients with grade 3-4 obstructive epiphora. Follow-up was conducted for 1-20 months (average, 11.3 months). The obstruction was at the lacrimal sac in six systems, at the junction between the lacrimal sac and the nasolacrimal duct in 60 systems, and at the nasolacrimal duct in four systems. The cause of the obstruction was idiopathic in all cases but was probably residual to dacryocystitis. RESULTS: Of these 70 procedures, stent placement was technically successful in 61 systems (87%). On long-term follow-up, 41 (67.2%) stents remained in place, with resolution or clinical improvement, and 18 (29.5%) stents were removed (because of occlusion in 17 systems), with stent malpositioning in the duct in six cases. There were seven cases of malpositioning in all. Statistical analysis was performed to evaluate patency, compare patency in properly positioned stents and malpositioned stents, and establish the relationship between malpositioning and the need for irrigation to maintain stent patency. Of the total 70 stents originally placed, 41 (58.6%) were still in place and functional at long-term follow-up. At 1 year, 73% of properly positioned stents remained patent versus 0% of improperly positioned stents. Median stent patency in the former group was 20 months and was 1 month in the latter group (P = .00002). Eleven percent of properly positioned stents required irrigation versus 57% of incorrectly positioned stents (P = .01). CONCLUSION: After follow-up for 1 year, recurrence of epiphora brought on by stent obstruction was 28%. Early stent blockage and the need for periodic irrigation may be indicative of malpositioning of the stent.

[Analysis of the use of prostate specific antigen (PSA) in a health area of the Community of Madrid]. / Análisis de la utilización del antígeno específico prostático (PSA) en un área sanitaria de la Comunidad de Madrid.

OBJECTIVES: To approach the local extent of PSA-use, and to check its yield in terms of prostate cancer (PC) detection. METHODS: All PSA-test records (1997-1999) were reviewed and testing rates calculated per 1000 person-years. Detection rate (PC) was also estimated and referred to our PC prevalence study using the odds ratio as instrument for comparison. RESULTS: Testing rate in the general population was 21.6/1000 person-years. PC detection rate was 1.76% (1.28 inside the prevalence study). For every CP detected in the general population with a PSA ranging 4-10 ng/ml, 2.39 (OR = 2.39) were detected in the prevalence study (OR = 4.48 for the PSA range > 10 ng/ml). CONCLUSIONS: PSA-testing in our setting is high. PC detection rates were lower than expected.

Assessment of CO2 arteriography in arterial occlusive disease of the lower extremities.

PURPOSE: To compare the diagnostic ability and usefulness of carbon dioxide arteriography with that of angiography using iodinated contrast medium in ischemia of the lower extremities. METHODS: Between April 1997 and February 1998 arteriography was performed systematically in 50 consecutive patients (42 men, eight women; average age, 65 years), who presented with peripheral vascular disease of the arteries of the lower extremities, with use of both CO2 and iodinated contrast medium. Untoward events that occurred during the examinations and the resulting clinical problems were recorded. Subsequently, two radiologists carried out a double-blind evaluation of the images obtained for each segment (aorta, pelvis, thighs, knees, legs, and feet) using the two different contrast agents to diagnose the arterial condition (normal, aneurysm, stenosis, and occlusion). Afterward, the two types of study performed for each patient were compared to assess the overall quality of CO2 arteriography as opposed to arteriography performed with use of iodinated contrast material. RESULTS: Forty-eight percent of the patients reported discomfort during the CO2 examinations and 18% of the studies had to be discontinued as a result. When problems relating to poor image quality were included, only 36% of the arteriograms obtained with use of CO2 were complete. Evaluation was possible in only 25% of CO2 studies of the feet. On average, the overall quality of the arteriograms obtained with use of CO2 was insufficient for diagnosis. CONCLUSION: In the authors' experience, CO2 arteriography cannot replace procedures performed with use of iodinated contrast medium for routine examination of ischemia of the lower limbs. In most cases, because of lower tolerance to the procedure and poorer image quality, CO2 imaging was not of sufficient quality to permit diagnosis, particularly at the infrapopliteal level.

[Incidence of pneumonia due to mechanical ventilators in relation to external circuit changes in the respirator]. / Incidencia de neumonía asociada a ventilación mecánica en relación al cambio de circuitos externos del respirador.

Pneumonia is one of the infections of highest relevancy in Intensive Care Units, and according to the incidence of pneumonia associated to mechanical ventilation, the frequence of the ventilator external circuits change is still a topic of discussion. We decided to modify the protocol of change in our unit, from doing it every 48 hours to every 7 days. We performed a prospective study in 108 patients attended in a Polyvalent ICU who underwent mechanical ventilation during more than 24 hours. We formed two groups, in Group 1 we changed circuits every 48 hours and in Group 2 the circuits were changed every 7 days, without using bacterian filters in any of the groups. The results obtained in Group 1 were of an accumulated incidence of pneumonia associated to mechanical ventilation of 18% and density of incidence of 21.1 pneumonias per 1000 days of mechanical ventilation. In Group 2 we obtained an accumulated incidence of pneumonia associated to mechanical ventilation of 19% and a density of incidence of 20.5 pneumonias per 1000 days of mechanical ventilation. In the analysis of data there were no significant statistic differences between both groups. The cost of respirator external circuits was diminished in 27% in Group 2. We conclude that the circuits change every 7 days does not produce an increase in the frequence of pneumonia associated to mechanical ventilation, with the expense of the respirator external circuits being remarkably reduced.

[Expectant treatment of superficial bladder tumors: preliminary results]. / Tratamiento expectante de los tumores vesicales superficiales: resultados preliminares.

A group of patients presenting with superficial bladder tumors (Ta-T1, G1-G3) was entered in a surveillance program following TUR. A standard univariative analysis was used to study tumor and patient prognostic factors to recurrence and progression. To define further the importance of each variable, a multivariative analysis was performed. Regardless of stage, grade and sex, patients with multiple tumors and/or size > or = 2 cm were particularly exposed to frequent recurrences. Early recurrences (before month 9) were associated with high recurrence rates. Considering the results of topical chemotherapy and toxicity of BCG immunotherapy, surveillance could be and option for superficial bladder tumors, reserving adjuvant therapy for large, multiple or early recurrence.