ABSTRACT
BACKGROUND: The preeclampsia is a multisystemic syndrome that occupied the first cause of maternal and fetal mortality around the world. Epidemiologic studies shown both mother and father contribute at the same risk for preeclampsia. OBJECTIVE: To determinate if there is an association between preeclampsia and paternal age. MATERIAL AND METHOD: Preeclampsia-eclampsia patients and couples were analyzed in agree to "National High Blood Pressure Education Program Working Group" classification, and a control group constituted by normal pregnant women and couples was included. RESULTS: There were 27 cases with mild preeclampsia and her couples, 13 cases with severe preeclampsia and her couples and 40 controls conformed by normal pregnant women and her couples. The statistical analysis of variance of the ages shown that men from preeclamptic group had a greater variance in contrast with man of control group (p < 0.001; valor of F = 5.084). CONCLUSIONS: Although is not clear how paternal age interview in preeclampsia risk, the interaction between paternal-maternal imprinting and spermatic senescence, followed by shortened telomeres of chromosome, could be produce the inactivity of a whole network of signals implicated in disease aetiology.
Subject(s)
Eclampsia/epidemiology , Paternal Age , Pre-Eclampsia/epidemiology , Adult , Causality , Diabetes Mellitus/genetics , Female , Genomic Imprinting , Humans , Hypertension/genetics , Male , Maternal Age , Middle Aged , Models, Biological , Pilot Projects , Pregnancy , Risk , Young AdultABSTRACT
We present a case report of a patient that went to consultation for tumoración presence at level vulvar of a year of evolution, with size of 8 x 6 cm, accompanied by pain with the deambulación and manipulation, the out taking of tumoración biopsy, later on resection by means of vulvectomia simple left and the result anatomohistopatológico was corroborated that reported hemangioma fibrous esclerosante. The treatment and the evolution was favorable. You analyzes the case and their such complications as: infection of surgical wound and dehiscencia. Bibliography related with the topic was revised.
