1.
J Biol Regul Homeost Agents
; 34(1): 215-219, 2020.
Article
in English
| MEDLINE
| ID: mdl-32397696
2.
Chemistry
; 7(18): 3890-900, 2001 Sep 17.
Article
in English
| MEDLINE
| ID: mdl-11596931
ABSTRACT
The study of a variety of substituted sulfoxides as chiral auxiliaries in intermolecular Heck reactions of sulfinyldihydrofurans and sulfinylcyclopentenes with different iodoarenes is reported. In the presence of [Pd(OAc)2]/Ag2CO3 and a bidentate phosphine ligand, synthetically useful yields and asymmetric inductions were obtained. By far the best diastereoselectivities were obtained by the use of the palladium-coordinating O-(N,N-dimethylamino)phenylsulfinyl group. By final removal of the chiral auxiliary, these sulfoxide-stereocontrolled asymmetric Heck processes were applied to the enantioselective synthesis of 1-aryl-substituted and 1,3-diaryl-substituted dihydrofurans and cyclopentenes.