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1.
Rev cienc med Habana ; 20(1)ene.-abr. 2014.
Article in Spanish | CUMED | ID: cum-56944

ABSTRACT

Introducción: la definición exacta de la disfunción sexual femenina es objeto de polémica, aunque se admite que es relativamente frecuente. La expresión de su sexualidad se reconoce universalmente y debe tenerse en cuenta en el abordaje clínico de sus problemas.Objetivo: describir aspectos clínicos epidemiológicos de la disfunción sexual en mujeres de 15-49 años atendidas en las consultas de Ginecología de los policlínicos universitarios Luis Li Trijent y Marta Martínez Figuera del municipio de Guines.Métodos: investigación descriptiva, de corte transversal realizada durante el periodo comprendido entre diciembre del año 2011 hasta marzo del año 2012. La muestra estuvo conformada por 48 mujeres que cumplieron con criterios de inclusión previamente establecidos. Se determinó la presencia de disfunción sexual y su relación con diferentes variables sociodemográficas.Resultados: se demostró la presencia de disfunción sexual en las edades entre los 37-49 años. Los trastornos del deseo, excitación y satisfacción sexual fueron los tipos de disfunción más frecuentes. Los conflictos intrapsíquicos, los antecedentes de experiencias negativas, así como los problemas de pareja constituyeron los principales problemas psicológicos encontrados en las féminas estudiadas. Se comprobó la presencia de problemas médicos relacionados con la disfunción sexual fundamentalmente patologías uterinas y la utilización de anticonceptivos orales en el momento de la investigación.Conclusiones: se demostró la presencia de disfunción sexual en el 20, 83 por ciento las mujeres estudiadas. Se propone diseñar proyectos de intervención que capaciten a nuestros profesionales en el seguimiento y tratamiento adecuado de las disfunciones sexuales femeninas desde la atención primaria de salud (AU)


Introduction: the exact definition of female sexual dysfunction is embroiled in controversy, although it is recognized that it is relatively common. The expression of women's sexuality is universally recognized and must be considered in the clinical approach to their problems.Objective: to describe clinical and epidemiological aspects of sexual dysfunction in women aged 15-49 attended at Gynecology consultations of Luis Li Trijent and Marta Martínez Figuera university polyclinics of Güines municipality.Methods: a descriptive, cross-sectional research was conducted during the period from December 2011 to March 2012. The sample consisted of 48 women who met inclusion criteria previously established. The presence of sexual dysfunction and its relationship to different sociodemographic variables was determined.Results: the presence of sexual dysfunction was demonstrated in the ages between 37-49 years. Disorders of desire, arousal and sexual satisfaction were the most frequent types of dysfunction. Intrapsychic conflicts, antecedents of negative experiences and marital problems were the main psychological problems encountered in the studied females. It was verified the presence of medical problems related to sexual dysfunction primarily uterine pathologies and the use of oral contraceptives at the moment of the research.Conclusions: it was demonstrated the presence of sexual dysfunction in 20,83 per cent of the women studied. It is proposed to design intervention projects to train our professionals in monitoring and appropriate treatment of female sexual dysfunction from primary health care (AU)


Subject(s)
Adolescent , Young Adult , Adult , Middle Aged , Female , Humans , Sexual Dysfunction, Physiological/epidemiology , Primary Health Care
2.
Histopathology ; 59(6): 1183-93, 2011 Dec.
Article in English | MEDLINE | ID: mdl-22175898

ABSTRACT

AIMS: The World Health Organization lymphoma classification recognizes two different Epstein-Barr virus (EBV)-positive T-cell lymphoproliferative disorders of childhood: systemic EBV-positive T-cell lymphoproliferative disease of childhood, and hydroa vacciniforme-like lymphoma, which is more prevalent in Asia and Latin America. The aim of this study was to characterize six cases of paediatric EBV-positive peripheral T-cell lymphoma with distinct features. METHODS AND RESULTS: All cases were male, with a median patient age of 9 years (range: 5-17 years). Most of them presented suddenly with fever, weight loss, hepatosplenomegaly, peripheral lymphadenopathy, and high lactate dehydrogenase (LDH) levels. Moreover, gut, lung or soft tissues of the abdominal wall were also affected in four cases. Partial to total replacement of the lymph node by pleomorphic infiltration of atypical neoplastic cells was found in all cases. Vasculitis and geographical areas of necrosis were seen in three and four cases, respectively. Neoplastic cells showed expression of EBV-encoded RNA, T-cell markers (CD2 and CD3), and cytotoxic markers (TIA1, granzyme-B, and perforin). CD56 and T-cell receptor -γ were expressed in one case each. TCR-BF1, CD4, CD8 and anaplastic lymphoma kinase were negative. In all cases, the disease progressed rapidly, causing death of the patient, with a median survival of 7.1 months (range: 1-13 months). CONCLUSIONS: These cases probably represent a solid form of systemic EBV-positive T-cell lymphoproliferative disease of childhood, which requires identification and the development of appropriate therapy.


Subject(s)
Epstein-Barr Virus Infections/complications , Killer Cells, Natural/pathology , Lymphoma, T-Cell, Peripheral/pathology , Lymphoma, T-Cell, Peripheral/virology , Adolescent , Biomarkers, Tumor/analysis , Child , Child, Preschool , Humans , Immunohistochemistry , In Situ Hybridization , Lymphoma, T-Cell, Peripheral/metabolism , Male
3.
Obstet Gynecol ; 105(5 Pt 2): 1278-80, 2005 May.
Article in English | MEDLINE | ID: mdl-15863610

ABSTRACT

BACKGROUND: Uterine malignant mixed mesodermal tumor is a rare variant of uterine cancer. Data suggest that tamoxifen is involved in the pathogenesis. We report a case of a women in whom a malignant mixed mesodermal tumor was diagnosed while she was taking raloxifene, which is also a selective estrogen receptor modulator. CASE: A malignant mixed mesodermal tumor was diagnosed in a 64-year-old woman with a bicornuate uterus while she was taking raloxifene for osteoporosis prevention. Diagnosis had been delayed secondary to sampling of the other uterine horn. CONCLUSION: There may be an association between raloxifene and the development of malignant mixed mesodermal tumor. Special attention should be paid when attempting to sample the endometrium in patients with mullerian abnormalities.


Subject(s)
Mixed Tumor, Mullerian/chemically induced , Mixed Tumor, Mullerian/pathology , Raloxifene Hydrochloride/adverse effects , Selective Estrogen Receptor Modulators/adverse effects , Uterine Neoplasms/chemically induced , Uterine Neoplasms/pathology , Biopsy, Needle , Chemotherapy, Adjuvant , Combined Modality Therapy , Female , Follow-Up Studies , Humans , Hysterectomy/methods , Immunohistochemistry , Middle Aged , Mixed Tumor, Mullerian/therapy , Neoplasm Staging , Osteoporosis, Postmenopausal/diagnosis , Osteoporosis, Postmenopausal/drug therapy , Ovariectomy/methods , Radiotherapy, Adjuvant , Raloxifene Hydrochloride/therapeutic use , Selective Estrogen Receptor Modulators/therapeutic use , Treatment Outcome , Uterine Neoplasms/therapy
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