ABSTRACT
Se presenta el caso clínico de un varón de 80 años diagnosticado de leiomiosarcoma testicular primario, a raíz de alteraciones del perfil hepático en analítica sanguínea y lesiones ocupantes de espacio (LOE) hepatoesplénicas en ecografía abdominal. En primer lugar, se realizó punción de lesión hepática y posteriormente orquiectomía radical, revelando concordancia histológica, compatible con leiomiosarcoma intratesticular. Presentamos el caso clínico debido a la rareza de ese tipo de tumores, sobre todo en estadio III, y su peculiar diagnóstico, tras la detección de alteración hepática tanto analítica como ecográfica
We present a case of an 80-year-old male diagnosed with primary testicular leiomyosarcoma due to the detection of hepatic profile analytical alterations and hepatosplenic space-occupying lesions in abdominal ultrasound. Puncture of hepatic lesion was performed first and radical orchiectomy later, revealing histological concordance, compatible with intratesticular leiomyosarcoma. We present the case due to the uncommon of this type of tumors, especially in stage III and its peculiar diagnosis, secondary of hepatic alteration, both analytic and ultrasound.
Subject(s)
Humans , Male , Aged, 80 and over , Testicular Neoplasms , Orchiectomy , Leiomyosarcoma , Liver/abnormalities , Liver Neoplasms , Biopsy , Ultrasonography , NeoplasmsABSTRACT
Pegylated interferon and ribavirin is the treatment of choice in patients with chronic hepatitis C infection. The most common side effects of interferon therapy are flu-like symptoms and psychiatric disorders. Pneumonitis is a less frequent complication associated with non-negligible mortality. We herein report a case of interferon associated pneumonitis in a patient with non-severe clinical symptoms and a normal chest radiography. Physicians should be aware of this entity during the differential diagnosis of respiratory symptoms in patients receiving treatment with interferon due to its high morbimortality and good resolution and outcome after drug withdrawal.
Subject(s)
Antiviral Agents/adverse effects , Hepatitis C/complications , Interferon-alpha/adverse effects , Lung Diseases, Interstitial/chemically induced , Polyethylene Glycols/adverse effects , Antiviral Agents/therapeutic use , Hepatitis C/drug therapy , Humans , Interferon alpha-2 , Interferon-alpha/therapeutic use , Lung Diseases, Interstitial/complications , Lung Diseases, Interstitial/diagnostic imaging , Male , Middle Aged , Polyethylene Glycols/therapeutic use , Recombinant Proteins , Tomography, X-Ray ComputedABSTRACT
OBJECTIVE: Members of "Asociación de Ecografía Digestiva" decided to carry out a multicenter retrospective study on fine-needle aspiration biopsy for pancreatic space-occupying lesions under ultrasonographic guidance and via the percutaneous route in order to assess this technique s performance versus endoscopic ultrasound-guided biopsy. SUBJECTS: 10 hospitals for a total of 222 patients with suspiciously malignant, 8-120-mm pancreatic lesions were included in the study. RESULTS: The analysis of results shows a sensitivity of 89%, a specificity of 98%, a positive predictive value of 99%, and a negative predictive value of 74%, for an overall diagnostic accuracy of 91%. No major complications occurred. CONCLUSION: Percutaneous fine-needle aspiration for pancreatic lesions is highly cost-effective and has few and mild complications.
Subject(s)
Endoscopy, Gastrointestinal , Pancreas/diagnostic imaging , Pancreas/pathology , Pancreatic Diseases/diagnostic imaging , Pancreatic Diseases/pathology , Adult , Aged , Aged, 80 and over , Biopsy, Fine-Needle/methods , Female , Humans , Male , Middle Aged , Retrospective Studies , UltrasonographyABSTRACT
Spontaneous bacterial peritonitis is a well known complication in cirrhotic patients with ascites. The etiological spectrum is broad. We report a case of spontaneous bacterial peritonitis due to Plesiomonas shigelloides.
Subject(s)
Gram-Negative Bacterial Infections/microbiology , Peritonitis/microbiology , Plesiomonas , Cefotaxime/therapeutic use , Gram-Negative Bacterial Infections/complications , Gram-Negative Bacterial Infections/diagnosis , Gram-Negative Bacterial Infections/drug therapy , Humans , Liver Cirrhosis, Alcoholic/complications , Male , Middle Aged , Peritonitis/complications , Peritonitis/drug therapySubject(s)
Bone Neoplasms/secondary , Intestinal Neoplasms/diagnosis , Lymphoma, B-Cell/diagnosis , Humans , Male , Middle AgedABSTRACT
We describe the case of a patient with hepatic cirrhosis treated with an intravenous infusion of vasopressin to control an upper digestive hemorrhage, who developed distance cutaneous necrosis and rhabdomyolysis. We review the other cases published in the international scientific literature and we discuss the possible pathogeny of these complications.
Subject(s)
Rhabdomyolysis/chemically induced , Skin/drug effects , Vasopressins/adverse effects , Gastrointestinal Hemorrhage/complications , Gastrointestinal Hemorrhage/drug therapy , Humans , Infusions, Intravenous , Liver Cirrhosis, Alcoholic/complications , Liver Cirrhosis, Alcoholic/drug therapy , Male , Middle Aged , Necrosis/chemically induced , Necrosis/pathology , Rhabdomyolysis/pathology , Skin/pathology , Vasopressins/administration & dosageABSTRACT
A patient is described who developed liver cirrhosis and variceal bleeding. After a continuous infusion of vasopressin rabdomyolysis occurred. Recovery of the clinical picture and of the muscle enzymes occurred 48 hours after cessation of therapy.
Subject(s)
Rhabdomyolysis/chemically induced , Vasopressins/adverse effects , Humans , Infusions, Intravenous , Male , Middle Aged , Vasopressins/administration & dosageABSTRACT
Two cases of diffuse peritoneal mesothelioma are reported. They were not associated with asbestos exposure and they presented as fever of unknown origin and ascitic syndrome, respectively. The literature is reviewed.
Subject(s)
Mesothelioma/diagnosis , Peritoneal Neoplasms/diagnosis , Aged , Biopsy , Female , Humans , Laparotomy , Male , Mesothelioma/pathology , Middle Aged , Peritoneal Neoplasms/pathology , Peritoneum/pathologyABSTRACT
Yersinia enterocolitica is a rare cause of systemic infections, including spontaneous bacterial peritonitis. Most reported cases have been in patients with iron overload or host defenses compromised by chronic illnesses. We report the case of an alcoholic patient with hemochromatosis who developed spontaneous bacterial peritonitis due to Yersinia enterocolitica.