ABSTRACT
PURPOSE: To evaluate 1-year changes of vault, anterior chamber angle width (ACAW) and intraocular pressure (IOP) after the implantation of implantable collamer lens (ICL) V4c in high myopic patients. METHODS: Sixty ICL V4c implantation surgeries were included. Patients underwent surgery between January 2014 and June 2017 at Ophthalmology Center Tecnolaser Clinic Vision®, Seville, Spain. All patients had a 12-month follow-up. A preoperative spherical equivalent between - 4.00 and - 15.00 D was established as inclusion criterion. ACAW and vault were measured with Pentacam single rotation Scheimpflug camera (Oculus Optikgeräte GmbH, Wetzlar, Germany). IOP was measured with CORVIS ST (Oculus Optikgeräte GmbH, Wetzlar, Germany). RESULTS: One-day vault was 553.17 ± 169.80 [268-975] µm; 12-month vault was 515.67 ± 176.46 [169-950] µm (p < 0.01). Preoperative ACAW was 36.85° ± 4.60° [26.7°-46.8°]; postoperative ACAW was 25.98° ± 3.85° [16.4°-32.6°] (p < 0.01). Preoperative IOP was 15.37 ± 1.58 [12.0-18.3] mmHg, postoperative IOP was 15.61 ± 1.60 [12.0-19.0] mm Hg (p = 0.35). CONCLUSIONS: ICL V4c lens experienced a progressive reduction of vault after 12-month follow-up. ACAW decrease was significant between preoperative and postoperative values. We propose to include a minimum preoperative ACAW and an IOP correction factor for lens size.
Subject(s)
Intraocular Pressure , Phakic Intraocular Lenses , Anterior Chamber , Follow-Up Studies , Germany , Humans , Lens Implantation, Intraocular , SpainABSTRACT
No disponible
Subject(s)
Humans , Burns/therapy , Burns, Electric/therapy , Eye Burns/therapy , Emergency Medical Services/statistics & numerical data , Emergency Treatment/methodsABSTRACT
PURPOSE: The goal of this study was to evaluate the experimental effectiveness of Regenerative Factor Rich Plasma (RFRP) of human blood versus Fetal Bovim Serum (FBS) and neuropeptide Substance P (SP) on corneal epithelium cell proliferation. METHOD: Rabbit corneal epithelium cell (CCL-60) growth was compared between different RFRP fractions, FBS and with the neuropeptide Substance P. The ability of the RFRP fractions and SP to revert the inhibitory effect of the CsA was also evaluated. RESULTS: All groups showed an increase (p<0.001) in corneal epithelial cell growth compared with the control group. The maximum capacity of cell growth was obtained with dilutions of 50% in the FBS, RFRP-I, RFRP -II, RFRP-III groups and with 100nM of SP. The highest growth was observed with 50% FBS, RFRP-I and RFRP-II. The group with SP and RFRP-III had significantly lower growth (p<0.001). When the NK1 receptor antagonist CsA was added at a dose of IC50, we found a significant decrease in cell growth (p<0.001) in all culture conditions, including the control group. The decrease was similar in all groups, but was especially pronounced in RFRP-II. RFRP I, II and III promoted growth more than SFB 10%. CONCLUSION: The RFRP of human blood promotes the growth of corneal epithelial cells in a significantly more efficient manner than FBS and SP. RFRP can be effective both in cell cultures and stem cell cultures.
Subject(s)
Cornea/metabolism , Epithelial Cells/metabolism , Plasma/chemistry , Serum/chemistry , Substance P/metabolism , Animals , Cattle , Cell Culture Techniques/methods , Cell Line , Cell Proliferation/drug effects , Culture Media/chemistry , Cyclosporine/chemistry , Humans , Neuropeptides/chemistry , Rabbits , Receptors, Neurokinin-1/chemistry , Stem Cells/cytologyABSTRACT
PURPOSE: To study the efficiency of the subconjunctival application of autologous regenerative factor-rich plasma (RFRP) in patients with different degrees of ocular alkali burns. METHODS: Thirty-five eyes of 35 patients with ocular alkali burns were analyzed. They were classified into moderate and relevance groups according to the severity of the burn. A control group was established for each with conventional topical medical treatment; subconjunctival regenerative factor rich plasma (RFRP) was applied to the other groups. A further group was added to the severe chemical burn group, which received autohemotherapy. The clinical evolution of the lesions and the period in which the pathology prevented the patient from working were studied; monitoring was carried out until the patient had healed. RESULTS: In the moderate chemical burns, there was a significant reduction in corneal and conjunctival epithelization times, sick leave duration, and healing time when the patients were treated with RFRP in comparison to the control group. With regard to the severe burns, significant reduction in time to corneal scarring in those treated with RFRP in comparison to traditional treatment was reported. RFRP showed, at least as effective and less side effects than the autohemotherapy. CONCLUSIONS: Subconjunctival infiltration with autologous RFRP can be considered an effective, straightforward, and economical form of treatment for burns of the ocular surface.
Subject(s)
Alkalies/antagonists & inhibitors , Burns, Chemical/therapy , Conjunctiva/physiology , Cornea/physiology , Eye Burns/chemically induced , Platelet-Rich Plasma , Wound Healing/physiology , Adult , Burns, Chemical/classification , Burns, Chemical/physiopathology , Disability Evaluation , Epithelial Cells/physiology , Eye Burns/classification , Eye Burns/physiopathology , Humans , Male , Regeneration , Sick Leave , Treatment OutcomeABSTRACT
América Central hacia el 2000 es la visión común de una serie de ensayos preparados por especialistas latinoamericanos que marcarán pautas para el futuro de la sociedad y la economía de los países centroaméricanos. La crisis económica y la guerra abierta han caracterizado el decenio de los años ochenta, ampliando a límite no conocidos fenómenos como la pobreza, el desplazamiento de la población, el endeudamiento externo, la inflación y la caída de las exportaciones tradicionales. Los avances en las negociaciones relacionadas con la paz en la subregión abren perspectivas para entrar en el decenio de los noventa a una etapa de reconstrucción y progreso, en la que los gobiernos del Istmo tomarán sobre sí la responsabilidad de su destino
Subject(s)
Economic Development/trends , Poverty/trends , Public Policy , Democracy , Population Dynamics , Economics , Gross Domestic Product , Income , Economic Indexes , Socioeconomic Factors , Central America , Unemployment , AgricultureABSTRACT
América Central hacia el 2000 es la vision comun de una serie de ensayos preparados por especialistas latinoamericanos que marcaran pautas para el futuro de la sociedad y la economía de los países centroamericanos. La crisis economica y la guerra abierta han caracterizado el decenio de los anos ochenta, ampliando a limite no conocidos fenomenos como la pobreza, el desplazamiento de la poblacion, el endeudamiento externo, la inflacion y la caida de las exportaciones tradicionales. Los avances en las negociaciones relacionadas con la paz en la subregion abren perspectivas para entrar en el decenio de los noventa a una etapa de reconstruccion y progreso, en la que los gobiernos del Istmo tomaran sobre si la responsabilidad de su destino
