Cytotoxic-antineoplastic activity of acetyl derivatives of prenylnaphthohydroquinone.

Several acetyl derivatives of prenylnaphthohydroquinone have been synthetized and evaluated for their cytotoxicity against A-549 human lung carcinoma and H-116 human colon carcinoma neoplastic cells. The IC50 values against A-549 are compared with those observed for previously reported unsubstituted derivatives.