ABSTRACT
PURPOSE: This study investigated short-term changes in body composition, handgrip strength, and presence of lymphedema in women who underwent breast cancer surgery. METHODS: Ninety-five women participated in a cross-sectional study, divided into two groups: Control (n=46), with healthy women, and Experimental (n=49), with women six months after breast cancer surgery. The Experimental Group was subdivided into right total mastectomy (RTM, n=15), left total mastectomy (LTM, n=11), right quadrant (RQ, n=13), and left quadrant (LQ, n=10). It was also redistributed among women with presence (n=10) or absence (n=39) of lymphedema. Presence of lymphedema, handgrip strength, and body composition were assessed. RESULTS: Trunk lean mass and handgrip strength were decreased in the Experimental Group. Total lean mass was increased in the LTM compared to RTM or LQ. Left handgrip strength in LTM was decreased compared to RTM and RQ and in LQ compared to RTM and RQ. Finally, total lean mass, trunk fat mass, trunk lean mass, right and left arm lean mass were increased in women with lymphedema. CONCLUSIONS: Breast cancer survivors have changes in their body composition and in handgrip strength six months after surgery; however, the interaction between the type of surgery and its impact is unclear. Furthermore, women who developed lymphedema in this period showed more significant changes in the body composition, but they were not enough to cause impairment in handgrip strength.
Subject(s)
Body Composition , Breast Neoplasms/surgery , Hand Strength , Lymphedema/physiopathology , Postoperative Complications/physiopathology , Cross-Sectional Studies , Female , Humans , Lymphedema/etiology , Mastectomy , Middle Aged , Postoperative Complications/etiology , Time FactorsABSTRACT
The study aimed to verify the physiological injury behavior by stretching the soleus muscle of rats, using a noninvasive experimental model. Twenty-four rats were used and divided into three groups of eight animals: control group (A), group that performed tetanus followed by electrical stimulation and a sudden dorsiflexion of the left paw performed by a device equipped with a mechanism of muscle soleus rapid stretching (B); and a group that only received the tetanus (C). Three days later, the animals were killed, and the soleus muscle was resected and divided into three segments. Morphological changes indicative of muscle damage appeared in all three segments of group B. In a lesser degree, similar changes were also detected in muscles subjected to only tetanus. This model was effective; reproducing an injury similar to what occurs in human sports injuries.
El estudio tuvo como objetivo verificar el comportamiento fisiológico de la lesión por estiramiento de los músculos soleos de ratas, utilizando un modelo experimental no invasivo. Veinticuatro ratas se utilizaron y se dividieron en tres grupos de ocho animales: Grupo A control; Grupo B se realiza tetanización por la estimulación eléctrica seguida de una repentina flexión dorsal de la pierna izquierda, realizado por un dispositivo equipado con un mecanismo rápido de estiramiento del músculo sóleo y Grupo C los animales sólo recibieron la tetanización. Tres días después, los animales fueron sacrificados, el músculo sóleo fue resecado y dividido en tres segmentos. Cambios morfológicos indicativos de daño muscular aparecieron en los tres segmentos del grupo B. En menor grado, cambios similares se detectaron en los músculos sometidos solamente al tetanización. El modelo fue eficaz, la reproducción de la lesión fue similar a lo que ocurre en las lesiones deportivas humanas.
