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Cavitary disease and quantitative sputum bacillary load in cases of pulmonary tuberculosis.
Palaci, Moises; Dietze, Reynaldo; Hadad, David Jamil; Ribeiro, Fabiola Karla Corrêa; Peres, Renata Lyrio; Vinhas, Solange Alves; Maciel, Ethel Leonor Noia; do Valle Dettoni, Valdério; Horter, Libby; Boom, W Henry; Johnson, John L; Eisenach, Kathleen D.
J Clin Microbiol ; 45(12): 4064-6, 2007 Dec.
Article in English | MEDLINE | ID: mdl-17928422

ABSTRACT

We examined sputum bacterial loads in adults with newly diagnosed tuberculosis using quantitative culture and time-until-positive (DTP) culture in BACTEC 460. Patients with cavitary disease had higher CFU levels than those without cavities and shorter DTPs. Within radiographic strata of moderately and far advanced tuberculosis, higher CFU counts were associated with cavitary disease.


Subject(s)
Mycobacterium tuberculosis/isolation & purification , Sputum/microbiology , Tuberculosis, Pulmonary/microbiology , Tuberculosis, Pulmonary/pathology , Adolescent , Adult , Colony Count, Microbial , Female , Humans , Male , Middle Aged
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