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Toxicon ; 49(3): 407-9, 2007 Mar 01.
Article in English | MEDLINE | ID: mdl-17161444

ABSTRACT

The species of the genus Palicourea (Rubiaceae family) is well-known for its toxicity towards animals, particularly livestock. This work reports the occurrence of skin irritation during the manipulation of Palicourea longiflora, considering the prevalence of the monofluoracetic acid (MFAA) and another toxic compound: methyl salicylate. The MFAA was identified by 19F-NMR and methyl salicylate by gas chromatography linked to mass spectrometry (GC/MS) analysis. Additionally, an anatomical study of leaves had been used to explain the mechanism of penetration of the toxic principles.


Subject(s)
Calcium Oxalate/toxicity , Irritants/toxicity , Rubiaceae/toxicity , Salicylates/toxicity , Animals , Brazil , Calcium Oxalate/chemistry , Crystallization , Gas Chromatography-Mass Spectrometry , Humans , Irritants/chemistry , Plant Extracts/chemistry , Plant Extracts/toxicity , Plant Leaves/chemistry , Rats , Rubiaceae/chemistry , Salicylates/chemistry
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