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1.
J S Afr Vet Assoc ; 82(1): 41-6, 2011 Mar.
Article in English | MEDLINE | ID: mdl-21826837

ABSTRACT

The objective of this study was to describe the changes in plasma glucose concentration in 20 severely injured dogs suffering from dog bite wounds over a period of 72 hours from the initiation of trauma. Historical, signalment, clinical and haematological factors were investigated for their possible effect on plasma glucose concentration. Haematology was repeated every 24 hours and plasma glucose concentrations were measured at 8-hourly intervals post-trauma. On admission, 1 dog was hypoglycaemic, 8 were normoglycaemic and 11 were hyperglycaemic. No dogs showed hypoglycaemia at any other stage during the study period. The median blood glucose concentrations at each of the 10 collection points, excluding the 56-hour and 64-hour collection points, were in the hyperglycaemic range (5.8- 6.2 mmol/l). Puppies and thin dogs had significantly higher median plasma glucose concentrations than adult and fat dogs respectively (P < 0.05 for both). Fifteen dogs survived the 72-hour study period. Overall 13 dogs (81.3 %) made a full recovery after treatment. Three of 4 dogs that presented in a collapsed state died, whereas all dogs admitted as merely depressed or alert survived (P = 0.004). The high incidence of hyperglycaemia can possibly be explained by the "diabetes of injury" phenomenon. However, hyperglycaemia in this group of dogs was marginal and potential benefits of insulin therapy are unlikely to outweigh the risk of adverse effects such as hypoglycaemia.


Subject(s)
Bites and Stings/veterinary , Blood Glucose , Dog Diseases/blood , Animals , Bites and Stings/blood , Bites and Stings/pathology , Dog Diseases/etiology , Dogs , Risk Factors , Time Factors
2.
J Small Anim Pract ; 48(5): 275-8, 2007 May.
Article in English | MEDLINE | ID: mdl-17425698

ABSTRACT

Spirocerca lupi is a nematode mainly affecting dogs but has been found in other animals, particularly carnivores. Anatomical areas of typical and aberrant migration vary. This report describes four cases of Spirocerca lupi causing neurological symptoms, similar to thoracolumbar disc syndrome, as a result of aberrant migration of the nematode into the spinal canal. In two of the cases, the nematode could be demonstrated intraoperatively. The third was discovered on post-mortem examination, while the fourth case displayed compelling evidence of Spirocerca lupi involvement. Surgical removal of the Spirocerca lupi nematode would be the treatment of choice in cases of spinal migration, with therapeutic and preventive treatment with doramectin instituted to treat remote sites and prevent re-infection. In areas endemic for spirocercosis, Spirocerca lupi should be considered as an important differential diagnosis in cases that are presented with clinical signs suggestive of a spinal cord lesion.


Subject(s)
Anthelmintics/therapeutic use , Dog Diseases/diagnosis , Ivermectin/analogs & derivatives , Spinal Canal/parasitology , Spirurida Infections/veterinary , Animals , Diagnosis, Differential , Dog Diseases/drug therapy , Dog Diseases/surgery , Dogs , Female , Ivermectin/therapeutic use , Male , Prognosis , Spirurida Infections/diagnosis , Spirurida Infections/drug therapy , Spirurida Infections/surgery , Thelazioidea/isolation & purification , Treatment Outcome
3.
J Small Anim Pract ; 47(1): 31-4, 2006 Jan.
Article in English | MEDLINE | ID: mdl-16417608

ABSTRACT

Double aortic arch denotes the persistence of both fourth aortic arches and has been reported as 'very rare' in the dog. Most reported cases have been seen in German shepherd dogs. An eight-week-old, male, 1.5-kg beagle presented with a three-week history of regurgitation and dyspnoea. A barium oesophagram showed severe oesophageal constriction cranial to the base of the heart, and a provisional diagnosis of a persistent right aortic arch was made. A left-sided fourth intercostal thoracotomy was performed. The ligamentum arteriosum was ligated and divided. The oesophagus was seen lying on the right-hand side of the aorta. Postoperatively, the puppy deteriorated and was euthanized. Postmortem revealed a double aortic arch entrapping both the oesophagus and trachea. The inexperienced surgeon could consider computed tomography or angiography to determine the exact vascular ring, and other possible concurrent vascular anomalies present, before surgery.


Subject(s)
Aorta, Thoracic/abnormalities , Dog Diseases/etiology , Dogs/abnormalities , Esophageal Stenosis/veterinary , Tracheal Stenosis/veterinary , Animals , Aorta, Thoracic/surgery , Dog Diseases/surgery , Dyspnea/etiology , Dyspnea/veterinary , Esophageal Stenosis/etiology , Esophageal Stenosis/surgery , Fatal Outcome , Gastroesophageal Reflux/etiology , Gastroesophageal Reflux/veterinary , Male , Tracheal Stenosis/etiology , Tracheal Stenosis/surgery
4.
J S Afr Vet Assoc ; 75(2): 85-9, 2004 Jun.
Article in English | MEDLINE | ID: mdl-15456164

ABSTRACT

This article describes the anaesthetic management and use of total intravenous anaesthesia (TIVA) for neurosurgery in 4 dogs. Propofol in conjunction with morphine was used for the maintenance of anaesthesia. Anaesthesia was induced with either thiopentone or propofol. The program Stelpump (a target-controlled infusion program) was run on a laptop and connected to a syringe driver via an RS 232 cable. The program was found to be reliable and safe for the administration of TIVA in dogs. Invasive monitoring was required in order to monitor cardiovascular changes during surgery. Ventilation was controlled to maintain the end-tidal carbon dioxide below 40 mm Hg. The anaesthesia was characterised by haemodynamic stability. The haemodynamic stability was probably the result of the choice of TIVA and balanced anaesthesia. Intracranial pressure and oedema was controlled with dexamethasone, mannitol and ventilatory management either in combination or alone. Three dogs survived to hospital discharge and 1 dog was euthanased 2 weeks later due to tumour metastasis. The development and characterisation of the anaesthetic effects of TIVA needs to be elucidated in order to provide clinicians with rational guidelines for the appropriate use of TIVA in veterinary medicine.


Subject(s)
Anesthesia, Intravenous/veterinary , Anesthetics, Intravenous/administration & dosage , Dogs/physiology , Narcotics/administration & dosage , Therapy, Computer-Assisted , Anesthesia, Intravenous/instrumentation , Anesthesia, Intravenous/methods , Anesthetics, Intravenous/pharmacokinetics , Animals , Blood Pressure/drug effects , Female , Male , Morphine/administration & dosage , Narcotics/pharmacokinetics , Neurosurgery/methods , Neurosurgery/veterinary , Propofol/administration & dosage , Retrospective Studies , Safety
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