[Comparative subcellular localization of para-hydroxylated derivatives of ephedrine and amphetamine in rat brain]. / Localisation subcellulaire centrale comparée des dérivés p hydroxylés de l'éphédrine et de l'amphétamine dans le cerveau du rat

Localisation of noradrenaline, hydroxyamphetamine, hydroxynorephedrine and hydroxyephedrine was studied in adrenergic granules of rat's brain in normal animals and in animals injected with hydroxy-6 dopamine. In normal animals the synaptosomes fixed noradrenaline, first and then, in decreasing order, hydroxynorephedrine, hydroxyephedrine and hydroxyamphetamine. Hydroxy-6 dopamine injection resulted in a decrease of fixation by synaptosomes, thus confirming the role of central false-transmitters of hydroxylated derivatives of amphetamine and ephedrine.