Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 1 de 1
Filter
Add more filters










Database
Language
Publication year range
1.
Pharmazie ; 58(2): 140-2, 2003 Feb.
Article in English | MEDLINE | ID: mdl-12641333

ABSTRACT

Tecostanine (1) was isolated from Tecoma stans leaves. Its sterochemistry was elucidated as well as its antihyperglycemic activity and its affinity to opioid and nicotinic receptors. The oxalate salt of 1 did not significantly affect blood glucose levels in normoglycaemic and hyperglycaemic rats. It did not appear to interact with opioid receptors (mu type) and showed only moderate affinity to the nicotinic receptor.


Subject(s)
Alkaloids/chemistry , Alkaloids/pharmacology , Bignoniaceae/chemistry , Hypoglycemic Agents/chemistry , Hypoglycemic Agents/pharmacology , Plants, Medicinal/chemistry , Terpenes/chemistry , Terpenes/pharmacology , Animals , Crystallography, X-Ray , Magnetic Resonance Spectroscopy , Male , Mexico , Models, Molecular , Molecular Conformation , Rats , Rats, Sprague-Dawley , Receptors, Nicotinic/drug effects , Receptors, Opioid/drug effects
SELECTION OF CITATIONS
SEARCH DETAIL
...