ABSTRACT
Two new pregnene derivatives 14beta-15alpha-dihydroxy-delta4pregnene-3,20 dione and 3beta-14beta,15alpha-16alpha hydroxy-20-oxo-delta5pregnene-tetra-ol, in addition to alpha- and beta-amyrin and beta-sitosterol, were isolated from Solenostemma argel leaves. The structures were established by extensive spectral analysis as well as comparison with reference materials.
Subject(s)
Biological Factors/chemistry , Biological Factors/isolation & purification , Plants, Medicinal/chemistry , Sitosterols/chemistry , Triterpenes/chemistry , Africa, Northern , Medicine, Traditional , Oleanolic Acid/analogs & derivatives , Plant Leaves/chemistry , Sitosterols/isolation & purification , Triterpenes/isolation & purificationABSTRACT
Three of ten sesquiterpene lactones isolated from the herb of Arctotis fastuosa (Asteraceae) belong to the heliangolide series. The first was identified as hirsutolide, the second is new and named dihydrohirsutolide, and the third, dichloromethyldihydrohirsutolide, is an artifact. The known degraded carotenoid loliolide was also isolated. Structures were established by spectroscopic methods including IR, 1D-/2D-1H-NMR, 13C-NMR, GHSQC, GHMBC, HREIMS and CD.
Subject(s)
Asteraceae/chemistry , Lactones/isolation & purification , Sesquiterpenes/isolation & purification , Lactones/chemistry , Molecular Structure , Sesquiterpenes/chemistry , Spectrum AnalysisABSTRACT
A new trinortriterpenoid, 1-epibrachyacarpone, was isolated from aerial parts of Cleome chrysantha. Its structure was elucidated as 1 by NMR investigations and X-ray crystallographic studies.
