ABSTRACT
Synovial sarcoma is a rare malignant mesenchymal neoplasm of youth with no benign counterpart. This cancer typically occurs about the knee and ankle joints. The involvement of the head and neck region is rare, and the laryngeal location is exceptional, which make the correct diagnosis challenging for the surgical pathologist and unanticipated for the clinician. Up to our knowledge, only 14 cases have been reported so far within this site. Here we add a new case in a 26-year-old Saudi man who presented with voice change and dysphagia, which are common symptoms of a more common benign condition in this site. The patient was operated and the histopathological diagnosis of synovial sarcoma was made, after which he received radiotherapy with no recurrence after 20 months. The correct diagnosis is crucial in such a case for proper management.
Subject(s)
Laryngeal Neoplasms/pathology , Sarcoma, Synovial/pathology , Adult , Humans , Laryngeal Neoplasms/diagnosis , Laryngeal Neoplasms/therapy , Male , Sarcoma, Synovial/diagnosis , Sarcoma, Synovial/therapyABSTRACT
Primary "xanthoma" of the bone is a rare lesion of unsettled histogenesis that may pose a diagnostic challenge owing to its wide range of differential diagnosis. Herein, we present a case of primary xanthoma of the right acromion in a middle aged woman who had no aberrant lipid metabolism or evidence of other pre-existing bone lesions. To our knowledge, this is the second reported case of a primary xanthoma involving the acromion in an adult.
