Granulomatous cystitis: a reversible lesion in children.

27 children with granulomatous cystitis associated with schistosomiasis and urinary tract infection were studied by urine culture and the direct immunofluorescence technique to detect the presence of antibody-coated bacteria (ACB). All patients had urinary schistosomiasis (100%); urine cultures of more than 10,000 bacteria/ml were present in 18 (66%) patients, and ACB-positive tests in 23 (85%) patients. Depending upon an ACB-positive test, children received full courses of antimicrobial and antibilharzial therapy. Follow-up after 3 months showed that granulomatous lesions subsided in 20 out of 23 (87%) children.