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Pharmazie ; 52(12): 926-9, 1997 Dec.
Article in English | MEDLINE | ID: mdl-9442556

ABSTRACT

Various new thiazolidinone and thioxoimidazolidinone derivatives were synthesized starting from 4,9-dimethoxy-5 H-furo[3,2-g][1]benzopyran-5-on-7-carboxaldehyde. The anticonvulsant activity of the synthesized compounds was evaluated. Most of the compounds showed anticonvulsant activity equal or superior to phenobarbital.


Subject(s)
Anticonvulsants/chemical synthesis , Imidazoles/chemical synthesis , Thiazoles/chemical synthesis , Animals , Anticonvulsants/pharmacology , Chemical Phenomena , Chemistry, Physical , Convulsants , Imidazoles/pharmacology , Khellin/chemistry , Male , Mice , Pentylenetetrazole , Phenobarbital/pharmacology , Seizures/chemically induced , Seizures/prevention & control , Thiazoles/pharmacology
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