Subject(s)
Carcinoma, Hepatocellular/complications , Cholestasis/complications , Cholestasis/etiology , Hemobilia/etiology , Liver Neoplasms/complications , Aged , Carcinoma, Hepatocellular/diagnosis , Carcinoma, Hepatocellular/surgery , Cholestasis/diagnosis , Cholestasis/surgery , Common Bile Duct/pathology , Common Bile Duct/surgery , Fatal Outcome , Hemobilia/diagnosis , Hemobilia/surgery , Humans , Liver Neoplasms/diagnosis , Liver Neoplasms/surgery , MaleABSTRACT
The comparative efficacy of roxatidine and ranitidine in the treatment of patients with acute duodenal ulcer was assessed at 4 and 6 weeks in this multicenter study. Ninety-four of 192 patients were given roxatidine in a single nightly dose of 150 mg, and 98 patients were given ranitidine in a single nightly dose of 300 mg. All the patients had endoscopically proven duodenal ulcer. Of the 171 assessable patients, ulcers were healed in 88% of the roxatidine group (73 of 83) and in 84% of the ranitidine group (74 of 88). No serious adverse events were reported in either group. We conclude that roxatidine 150 mg once daily is as effective and safe for the treatment of acute duodenal ulcer as ranitidine 300 mg once daily.
Subject(s)
Duodenal Ulcer/drug therapy , Histamine H2 Antagonists/therapeutic use , Piperidines/therapeutic use , Ranitidine/therapeutic use , Administration, Oral , Adult , Dose-Response Relationship, Drug , Double-Blind Method , Drug Administration Schedule , Duodenal Ulcer/pathology , Endoscopy, Digestive System , Female , Follow-Up Studies , Histamine H2 Antagonists/administration & dosage , Histamine H2 Antagonists/adverse effects , Humans , Male , Piperidines/administration & dosage , Piperidines/adverse effects , Ranitidine/administration & dosage , Ranitidine/adverse effects , Retrospective Studies , Safety , Treatment OutcomeSubject(s)
Cholestasis, Extrahepatic/parasitology , Fascioliasis/complications , Adult , Animals , Antiplatyhelmintic Agents/therapeutic use , Diethylcarbamazine/therapeutic use , Fascioliasis/drug therapy , Female , Filaricides/therapeutic use , Humans , Praziquantel/therapeutic use , Spirurida Infections/complications , Spirurida Infections/drug therapy , SpiruroideaABSTRACT
Ipsilateral fractures of the femur and tibia are usually considered a primary indication for internal fixation. A case of severely comminuted, open fracture of the distal femur and proximal tibia involving the knee which was managed conservatively is described here. This case is reported to make a plea for the trial of conservative management before opting for primary internal fixation of such complicated fractures. The conservative approach is strongly advocated when the essential requirements for internal fixation cannot be rigidly met.
